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Momentum Biotechnologies (formerly PureHoney Technologies)
Momentum Biotechnologies (formerly PureHoney Technologies) is listed as a small business research supplier in the Scientist.com network, with 2 sites in 2 countries.
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Sites
2
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
- Protein Glycosylation Mapping Technique Map glycosylation sites in proteins using liquid chromatography and mass spectrometry.
Cell Culture and Characterization
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
- Spent Media Analysis Measure chemical alterations, such as variations in amino acids, glucose, contaminants, and metabolites, in a cell culture medium throughout the culturing process.
Chemical and Compound Analysis
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
- Nano-High Performance Liquid Chromatography Separate and detect low levels of analytes.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 7 in Chemical and Compound Analysis
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Show all 86 services
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- Discovery Compound Screening Analytics Screening of an entire compound library directly against the drug target or in a more complex assay.
Discovery Chemistry
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
DNA & RNA
- Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
- Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.
- Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
- Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro ADME
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
Show all 14 in In Vitro ADME
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
- In Vitro ADME in Vitro ADME services
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- No Label Methods Use mass spectrometry to detect and identify non-radiolabeled drug intermediates in pre-clinical samples.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- HTS Assay Development Develop assays to use in high throughput screening.
- Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
In Vitro Pharmacology
- Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Histone Acetyltransferase (HAT) Assays Use biochemical, cell-based or in vivo assays to measure histone acetyltransferase activity.
- Histone Deacetylase (HDAC) Assays Use biochemical, cell-based or in vivo assays to measure histone deacetylase activity.
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
- Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Show all 16 in In Vitro Pharmacology
- Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
- Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
- Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
- Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
- Protein/Enzyme Targets For requesting Protein/Enzyme Targets
- Target Characterization Characterize potential drug targets during the drug discovery process.
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
- UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
- Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Ocular Pharmacokinetic (PK) Screening - Rabbit Conduct a pharmacokinetic screening study in rabbits that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
- LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
Show all 16 in Protein Sciences
- Phosphorylation Analysis Identify phosphorylation sites in target proteins.
- Protein Binding Determine drug-protein binding interactions
- Protein Identification Uncover or confirm the identity of a protein.
- Protein mapping Interrogate the entire sequence of a protein.
- Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.
- Quantitative MS Quantify small and large molecules in the pg/ml range
- SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Testing Services
- Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
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Germany 1 site
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
- Professional associations
- MassBio
- Website
- www.momentum.bio
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