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Longevity Biotech

Longevity Biotech is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Chemical and Compound Analysis

  • Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
  • Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
  • Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.

Chemistry, Manufacturing and Controls (CMC)

  • Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
  • Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
  • Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
  • Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
  • GI Fluid Stability Determine dosing and turnover of drug candidates in gastrointestinal fluids.
  • Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
  • Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
  • Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
  • Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
Show all 8 in In Vitro ADME 2 more
  • Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
  • Plasma Stability Assay Determine degradation rate of drug candidates in plasma.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Philadelphia 2 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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