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Certis Oncology Solutions
Certis Oncology Solutions is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
- Magnetic Resonance Imaging Use MRI to obtain chemical and physical information about molecules and map the internal structure of an object.
Show all 7 in Bioimaging
- Medical Imaging Visualize and analyze internal structures in animal models or patients.
Biomarkers
- Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Show all 13 in Biomarkers
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Show all 76 services
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Show all 8 in Cell Culture and Characterization
- Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
- Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Chemical and Compound Analysis
- Computed Tomography Visualize the internal features of solid objects.
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Clinical Trials
- Clinical Research Services Determine the safety and effectiveness of medications and medical devices.
- Clinical Trial Design Develop study-related protocols, case report forms (CRFs) and database tools for records management.
Companion Diagnostics
- Cervical Cancer CDx Design and validate companion diagnostics for cervical cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Data Science/Bioinformatics
- In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
- RWE/HEOR Machine Learning/AI Complex analytical approaches to find patterns and make predictions in RWE/HEOR projects
- Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
Disease Models
- Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
Human Biological Samples
- Custom PDX models For requesting Custom PDX models
- Existing PDX models For requesting Existing PDX models
- Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...
In Vitro ADME
- Multidrug Resistance Identify potential causes of drug-drug interactions.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Pharmacology
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
- RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Model Development
- Fresh Functional Human Tissue Efficacy Assays Use fresh functional human tissue to assess pre-clinical efficacy of test compounds.
- PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
- SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
- Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
- Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
Oncology Models
- Immuno-PDX Utilize the patient-derived xenograft for drug response profiling and biomarker discovery of immuno-oncology drug candidates.
- Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Oncology Xenografts Xenografts derived from oncological samples.
- Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
- Reproductive System PDX Patient derived xenografts relating to reproductive systems. This includes PDX from reproductive organs such as the Ovaries, Cervix, Breasts, Testes, Prostate, and Scrotum.
Show all 9 in Oncology Models
- Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
- Urinary System Xenografts Xenografts derived from organs of the Urinary system. This includes, but is not limited to, xenografts from the Bladder, Kidney, and Urethra.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Protein Identification Uncover or confirm the identity of a protein.
Safety Pharmacology
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
- Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
We provide oncology services to patients by developing individualized patient-derived orthotopic xenograft (PDOX) models for oncologists to tailor and optimize therapies. We also utilize these models to offer pre-clinical research services.
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