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Research supplier
Triclinic Labs
Triclinic Labs is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Chemical and Compound Analysis
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Chemical Stability Measure the stability of small molecules in solution.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- Diffuse Wave Spectroscopy Evaluate the micro-rheological properties of particles in opaque and concentrated media.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
- Energy Dispersive X-ray Spectroscopy Identify and estimate the elemental composition of a sample based on x-ray emission patterns.
Show all 17 in Chemical and Compound Analysis
- Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
- Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
- Hot Stage Microscopy (HSM) Visualize and characterize temperature-dependent phase transitions in pharmaceutical solids, polymers, and amorphous dispersions using polarized light microscopy coupled with a controlled thermal stage.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
- Small Angle X-Ray Scattering Obtain low-resolution structures of biopolymers in solution using an x-ray beam.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Coating Analysis Evaluate the coat properties of pharmaceuticals, polymers and other finished materials.
- Crystallization studies Crystallization studies
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Show all 10 in Chemistry, Manufacturing and Controls (CMC)
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- Polymorph Screening Screen for unwanted API forms resulting from the drug formulation process.
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 37 services
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Drug Development
- Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Protein Sciences
- Carbohydrate Structure Characterization Use analytical tools to elucidate carbohydrate structure and physiochemical properties.
- NMR Determine molecular and protein structure, and validate sample integrity.
- Protein Sequencing Determine the amino acid sequence of protein or peptide.
- X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Triclinic Labs is the leading service provider for pre-clinical solid-state development. Our scientists have more than a decade of proven polymorph, salt, cocrystal, and amorphous material development. Solid-form screening, selection, and problem solving services are combined with a full-service cGMP and non cGMP analytical and materials characterization laboratory. Our goal is to maximize and optimize the properties of your drug substance and drug product. We combine our physical and analytical chemistry expertise to maximize your pharmaceutical intellectual property and heavily support...
Show the full description
Triclinic Labs is the leading service provider for pre-clinical solid-state development. Our scientists have more than a decade of proven polymorph, salt, cocrystal, and amorphous material development. Solid-form screening, selection, and problem solving services are combined with a full-service cGMP and non cGMP analytical and materials characterization laboratory. Our goal is to maximize and optimize the properties of your drug substance and drug product. We combine our physical and analytical chemistry expertise to maximize your pharmaceutical intellectual property and heavily support patent prosecution and litigation efforts.
- Professional associations
- AAPS, ACS
- Website
- tricliniclabs.com
Work with Triclinic Labs on Scientist.com
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