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Bit Bio Ltd

Bit Bio Ltd is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Biomarkers

  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.

Cell Culture and Characterization

  • 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
  • Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
  • Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
  • Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
  • Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.

Disease Models

  • General Pain Models Measure therapeutic endpoints in animal models of general pain.
  • Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
  • Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
  • Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
  • Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
  • Pain Models Test therapeutic efficacy of drug candidate in pain model.
Show all 8 in Disease Models 2 more
  • Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
  • Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
Show all 33 services 20 more

Human Biological Samples

  • Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
  • FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
  • HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
  • Human iPSC's For requesting human sourced induced pluripotent stem cells.

In Vitro Assays

  • Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.

In Vitro Pharmacology

  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
  • In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
  • In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
  • In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
  • In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
  • Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
Show all 7 in In Vitro Pharmacology 1 more
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

In Vitro Toxicology

  • Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
  • Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.

Oncology Models

  • Muscle Wasting Models Measure therapeutic endpoints in animal models of muscle wasting.

Safety Pharmacology

  • Microelectrode Array Neurotoxicity Assays Use microelectrode array to measure neurotoxicity-related activities.

Testing Services

  • In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.

Other services

  • In Vitro Neurodegenerative Disease Platform Use an IVND platform to screen different compounds/drugs in a finely controlled synaptopathies scenario.
Website
bit.bio

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Cambridge 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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