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Bright Line Research
Bright Line Research is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
Biomarkers
- Autoantibody Testing Screen for the presence of an autoimmune disorder.
- Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Chemistry, Manufacturing and Controls (CMC)
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Glycobiology Study the structure biosynthesis and biology of carbohydrates
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
In Vitro Toxicology
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cytotoxicity Test for effects on cell viability and proliferation
- Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
Show all 21 services
Lab Supplies, Facilities, and Equipment
- Lab Equipment Mechanical Design Obtain custom laboratory equipment modification and/or production.
Nanotechnology
- Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Carbohydrate Structure Characterization Use analytical tools to elucidate carbohydrate structure and physiochemical properties.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Bright Line Research offers protein microarray production, multiplex assay development, and label-free binding analysis and cell-based assay services. Our specialty is label-free cell-based assays, including single-cell resolution attachment, morphology, proliferation, motility, and wound-healing (scratch) tests. We've been doing this (immunoassay development, micro-arraying and label-free surface analysis) for over twenty years, in the service of our own projects, and now we use this experience and our passionate curiosity to: Completely absorb and understand your scientific and financial...
Show the full description
Bright Line Research offers protein microarray production, multiplex assay development, and label-free binding analysis and cell-based assay services. Our specialty is label-free cell-based assays, including single-cell resolution attachment, morphology, proliferation, motility, and wound-healing (scratch) tests.
We've been doing this (immunoassay development, micro-arraying and label-free surface analysis) for over twenty years, in the service of our own projects, and now we use this experience and our passionate curiosity to:
- Completely absorb and understand your scientific and financial goals. Our keenly targeted projects will answer your questions.
- Show you what you've never seen before, true label-free real-time imaging of your multiplex arrays and cell-surface interactions.
- Deliver the best-working assays possible by optimizing every step, not just the amplified endpoint.
- Website
- www.brightlineresearch.com
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