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InVivo Biosystems
InVivo Biosystems is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Cell Culture and Characterization
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
Discovery Chemistry
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
Disease Models
- Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
- Excitotoxicity Models Measure therapeutic endpoints in animal models with excitotoxic pathology.
- Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
- In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Show all 9 in Disease Models
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
- Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
DNA & RNA
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
- Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
- RNAi Pathway Analysis Use high-throughput RNAi genetic screens to elucidate relevant signaling pathways.
Show all 39 services
General in vivo Toxicology
- Dose Range Finding Study - Other Species Conduct a study to determine the dose range of your compound in other species.
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.
In Vitro Toxicology
- Zebrafish Embryo Toxicity Use a single animal species to create one models of toxicity.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Custom Model Development Develop a custom disease model.
- Disease Model Database For sourcing disease models.
- Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.
- Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Show all 7 in Model Development
- Zebrafish Animal Model Model human disease and development in zebrafish.
Non-Human Biospecimen
- Zebrafish Cells, Tissues, and Biofluids Acquire fresh or frozen cells, tissues, and biofluids including but not limited to whole blood, PBMCs, tissue slides, sperm, etc.
Oncology Models
- Muscle Wasting Models Measure therapeutic endpoints in animal models of muscle wasting.
Other Specialty Toxicology
- Ocular Phototoxicity Study - Other Species Conduct a study to determine the extent to which your compound is capable of producing phototoxic side effects in ocular tissues of other species.
- Phototoxicity Determine whether drug treatment causes light-activated toxic effects.
Pharmacology
- In Vivo Pharmacology Study the effects of drug candidates in animal models
Scientific Data Services
- In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.
- Pharmaco-genomics Genetic polymorphism contribution to inter-individual variability in drugs' responses and/or adverse events.
- Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.
Specialty Dosing Routes
- Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Testing Services
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
Other services
- In Vitro Neurodegenerative Disease Platform Use an IVND platform to screen different compounds/drugs in a finely controlled synaptopathies scenario.
- Website
- invivobiosystems.com
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
Supplier diversity
SAM.gov small-business designations
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
Work with InVivo Biosystems on Scientist.com
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