Dana Farber Cancer Institute - Tumor Imaging Metrics Core

The Tumor Imaging Metrics Core provides standardized, consistent, longitudinal radiological measurements to evaluate therapeutic response for DF/HCC clinical trials. Services include accurate, consistent, and timely analysis of CT, MR, and PET/CT imaging studies. Measurements available include linear (RECIST, WHO, Cheson), volumetric measures for CT or MR scans, and Standardized Uptake Value (SUV) for PET scans. Results of analyses are offered on a password-protected secure web-based report. This core also provides an independent service with verifiable measurement of treatment response for patients enrolled in trials, and serves as a centralized, computerized resource to facilitate efficient internal or external auditing.

The TIMC:

Makes reliable, quantitative, longitudinal measurements (such as linear dimension, RECIST, volume, function, etc.) of lesions from serial MRI, CT, and PET scan images
Presents results of analyses on a password protected secure web-based report
Provides an independent service, with verifiable measurement of treatment response for patients enrolled in cancer center trials
Serves as a centralized, computerized resource to facilitate efficient internal or external auditing
Reliable tracking of changes in lesion size or function is essential for clinical trials that use radiological measurements as surrogate endpoints. The Tumor Metrics Core provides a service for managing these images, making measurements in a routine, reliable, and centralized way, and making results available to investigators efficiently.