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Hera BioLabs
Hera BioLabs is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.
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Sites
3
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Biomarkers
- Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
Cell Culture and Characterization
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Disease Models
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
- Hematopoiesis Models Measure therapeutic endpoints in animal models of hematopoiesis.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
Show all 9 in Disease Models
- Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
- Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
- Weanling Rat Use a single animal species to create one or more disease models for anemia.
Show all 83 services
DNA & RNA
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
In Vitro ADME
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Show all 7 in In Vitro ADME
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Assay Development Construct or create new assays or modify existing ones.
- Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
Show all 13 in In Vitro Assays
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
- Glucose Release Assay Determine free glucose levels in biological samples.
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
- Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
- In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
- In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
Show all 11 in In Vitro Pharmacology
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
- PARP Assays Use biochemical, cell-based or in vivo assays to measure PARP activity.
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
- Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
- Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
- Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
- PiggyBac Transgenic Mouse Service Obtain single-copy transgenic embryos with consistent expression of any desired transgene.
- Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
Show all 10 in Model Development
- SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
- SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
- Zucker Rat Use a single animal species to create one or more disease models for cachexia.
Oncology Models
- Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
- Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
- Murine Adenocarcinoma 16 (MAC16) Murine Test for therapeutic efficacy of drug candidates in muscle wasting models.
- Noble Rat Use a single animal species to create one or more disease models for hematopoiesis.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Oral Xenograft Measure therapeutic endpoints in oral cancer models as well as cancer models related to the Pharynx.
Show all 10 in Oncology Models
- Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
- Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
- T11 (Breast Cancer) Measure therapeutic endpoints in animal models of breast cancer.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
REACH Services
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Other services
- New Request
- Website
- www.herabiolabs.com
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
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