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Hera BioLabs

Hera BioLabs is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 3
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Bioimaging

  • In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
  • Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.

Biomarkers

  • Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
  • Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.

Cell Culture and Characterization

  • Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
  • Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Clinical Consulting

  • Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...

Disease Models

  • Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
  • Hematopoiesis Models Measure therapeutic endpoints in animal models of hematopoiesis.
  • In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
  • Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
  • Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
  • Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
Show all 9 in Disease Models 3 more
  • Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
  • Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
  • Weanling Rat Use a single animal species to create one or more disease models for anemia.
Show all 83 services 67 more

DNA & RNA

  • CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
  • Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.

In Vitro ADME

  • CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
  • CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
  • CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
  • Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
  • Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
  • Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Show all 7 in In Vitro ADME 1 more
  • Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.

In Vitro Assays

  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Assay Development Construct or create new assays or modify existing ones.
  • Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
  • Cell Proliferation Measure cell number, cell viability and cell division.
Show all 13 in In Vitro Assays 7 more
  • Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
  • Glucose Release Assay Determine free glucose levels in biological samples.
  • High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
  • Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
  • Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
  • Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

In Vitro Pharmacology

  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
  • In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
  • In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
  • In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.
  • In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
Show all 11 in In Vitro Pharmacology 5 more
  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.
  • Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
  • PARP Assays Use biochemical, cell-based or in vivo assays to measure PARP activity.
  • Target Identification Identify the target(s) of a biologically active substance.
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

In Vitro Toxicology

  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.

In Vivo Pharmacokinetics

  • In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
  • Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
  • Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.

Model Development

  • Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
  • Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
  • Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
  • Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
  • PiggyBac Transgenic Mouse Service Obtain single-copy transgenic embryos with consistent expression of any desired transgene.
  • Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
Show all 10 in Model Development 4 more
  • SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
  • SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
  • Transgenic Models Create animal models engineered for use in a specific therapeutic area.
  • Zucker Rat Use a single animal species to create one or more disease models for cachexia.

Oncology Models

  • Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
  • Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
  • Murine Adenocarcinoma 16 (MAC16) Murine Test for therapeutic efficacy of drug candidates in muscle wasting models.
  • Noble Rat Use a single animal species to create one or more disease models for hematopoiesis.
  • Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
  • Oral Xenograft Measure therapeutic endpoints in oral cancer models as well as cancer models related to the Pharynx.
Show all 10 in Oncology Models 4 more
  • Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
  • Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
  • T11 (Breast Cancer) Measure therapeutic endpoints in animal models of breast cancer.
  • Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Protein Sciences

  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.

REACH Services

  • OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.

Target Animal and Human Food Safety

  • Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.

Other services

  • New Request  

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Lexington 3 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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