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Beantown Biotech

Beantown Biotech is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Antibodies

  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Immunodetection Use antibodies to identify a protein or antigen.

Biomarkers

  • Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
  • Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Show all 9 in Biomarkers 3 more
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • Single Cell Isolation Isolate single cells for subsequent single-cell analysis.

Cell Culture and Characterization

  • 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Cell Culture Culture primary or immortalized cell lines.
  • Cell Line Construction Create new recombinant cell lines to exact specifications.
  • Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Show all 63 services 50 more

Chemical and Compound Analysis

  • Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
  • UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

Clinical Consulting

  • Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

DNA & RNA

  • DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
  • Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
  • qPCR Analysis Measure the accumulation of PCR products in real time.
  • Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
  • Recombinant Nucleosomes Use as substrates in histone methyltransferase or acetyltransferase assays.
  • RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
Show all 8 in DNA & RNA 2 more
  • RNA Extraction Isolate total RNA or mRNA from cells or tissues
  • Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.

Human Biological Samples

  • Human Whole Blood Acquire fresh/frozen normal whole blood based on patient demographics and history.

In Vitro Assays

  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Assay Development Construct or create new assays or modify existing ones.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • HTS Assay Development Develop assays to use in high throughput screening.
Show all 9 in In Vitro Assays 3 more
  • Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
  • Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

In Vitro Pharmacology

  • ATP Competitive Study Determine whether or not a compound is competitive with ATP.
  • Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
  • G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
  • Histone Acetyltransferase (HAT) Assays Use biochemical, cell-based or in vivo assays to measure histone acetyltransferase activity.
  • Histone Deacetylase (HDAC) Assays Use biochemical, cell-based or in vivo assays to measure histone deacetylase activity.
Show all 20 in In Vitro Pharmacology 14 more
  • Human BCL Assays Use biochemical, cell-based or in vivo assays to measure BCL activity.
  • Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
  • In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
  • Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
  • Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
  • PARP Assays Use biochemical, cell-based or in vivo assays to measure PARP activity.
  • Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
  • Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
  • Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
  • Protease Assay Measure protease activity in biochemical and cell-based assays.
  • Reversibility Study Determine whether or not a compound inhibits an enzyme reversibly.
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
  • Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
  • Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.

In Vitro Toxicology

  • ADCC and CDC Assay Services Measure toxicity of antibodies.
  • Cytotoxicity Test for effects on cell viability and proliferation

Protein Sciences

  • Cytokines Find recombinant cytokines or cytokine assays.
  • Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

Other services

  • New Request  

Service areas:

Biology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Billerica 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Beantown Biotech is a Contract Drug Discovery Research Organization offering Assay Development, High Throughput Screening and Lead Optimization. We offer radiometric assays and a wide variety of other in vitro and cell-based screening platforms.

Website
www.beantownbiotech.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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