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Avance Biosciences
Avance Biosciences is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Agricultural Sciences Research & Development
- Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties
Antibodies
- Immunodetection Use antibodies to identify a protein or antigen.
Biomarkers
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
Chemical and Compound Analysis
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Compendial test methods Run Compendial test methods (e.g., KF)
- ICH-compliant stability testing Perform ICH-compliant stability testing
Show all 54 services
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- Clinical Responder Analysis, Patient Stratification The process of identifying patients that are more likely to respond positively to a drug.
DNA & RNA
- Amplicon 16s rRNA Sequencing Identify and compare bacteria present within a given sample.
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
- Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
Show all 19 in DNA & RNA
- NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
- Plasmid Retention Assay Determine the percentage of cells in a sample that contain plasmids with a selectable marker.
- Poly (A) tail Length Profiling (PAL-Seq) Conduct high-throughput sequencing of individual mRNA poly (A) tails.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
- TCR Repertoire Sequencing Analyze the T cell receptor repertoire by means of next-generation sequencing.
- Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.
- Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
In Vitro ADME
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Other Specialty Toxicology
- Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety
- Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
- Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.
Protein Sciences
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Scientific Data Services
- Small RNA Gene Expression Quantify and analyze miRNA, piRNA, siRNA as well as other small nuclear RNAs from small-RNA-seq raw input data sets.
Testing Services
- Microbiological Sterility Testing Test the presence of viable microorganisms.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Avance Biosciences offers DNA sequencing, quantitative PCR (qPCR), and molecular biology services in compliance with relevant regulations of US FDA (cGMP/GLP), European, and Japanese regulatory agencies. We also provide non-regulated services, including next generation sequencing, to academic and industrial researchers.
- Website
- avancebio.com
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