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Gifford Bioscience Limited
Gifford Bioscience Limited is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
Discovery Chemistry
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
Disease Models
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
- Receptor Occupancy Models Determine the effective dose and concentration needed to reach effective levels in a given tissue.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
- Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Show all 30 services
In Vitro Pharmacology
- Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
- Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
Show all 14 in In Vitro Pharmacology
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
- Target Characterization Characterize potential drug targets during the drug discovery process.
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
- Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
Pharmacology
- In Vivo Pharmacology Study the effects of drug candidates in animal models
Protein Sciences
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
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United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Preclinical and discovery-stage contract research in receptor pharmacology. Core capabilities include radioligand binding assays, receptor occupancy assays, cell-based uptake and release assays and receptor autoradiography. We employ 'gold standard' radiometric methods in our studies to ensure maximum sensitivity and robustness.
- Website
- www.giffordbioscience.com
Work with Gifford Bioscience Limited on Scientist.com
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