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Research supplier
EpigenDx
EpigenDx is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Research & Development
- Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Multiplex Circulating miRNA Assay Profile miRNAs directly from just 10 μl of crude biofluid or 0.1 ng of purified RNA.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
Show all 7 in Biomarkers
- Whole Transcriptome Amplification Amplify total RNA from a single cell.
Chemical and Compound Analysis
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Clinical Trials
- Clinical Research Services Determine the safety and effectiveness of medications and medical devices.
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
Disease Models
- Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
Show all 45 services
DNA & RNA
- Bisulfite Seq DNA Methylation Analysis Determine DNA methylation status at single-base resolution
- Bisulfite Sequencing (RRBS) Analyze genome-wide methylation profiles on a single nucleotide level.
- ddPCR-Based Plasma Genotyping Perform noninvasive tumor genotyping.
- Digital Polymerase Chain Reaction Obtain improved absolute target quantification and rare allele detection compared to conventional qPCR.
- DNA Hydroxy Methylation Seq Use epigenetic services to analyze genome-wide DNA hydroxymethylation.
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
Show all 27 in DNA & RNA
- Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
- Methylation Specific PCR Determine the methylation status of a CpG site without the need for base-specific endonucleases.
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
- mtDNA Sequencing Use next-generation sequencing (NGS) technology to detect and analyze mitochondrial mutations.
- NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
- Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.
- SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
- Targeted Bisulphite Sequencing Reveal changes in DNA methylation associated with nuclear reprogramming.
- Targeted Sequencing/Resequencing Detect variations in a genome subset.
- Whole Genome Bisulphite Seq Profile genome-wide DNA methylation.
- Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Scientific Data Services
- Epigenomics Data Analysis Quantify and analyze DNA methylation and/or DNA binding protein data sets.
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
EpigenDx is a genomic and epigenomic research company dedicated to providing superior products and laboratory services. Our technical expertise and focus on quality and rapid turnaround time have made us a dependable partner to our customers worldwide since 2006. EpigenDx is the world-wide leading Pyrosequencing service provider in the biotechnology industry. Our lab has more than fifteen years of expertise in Pyrosequencing technology and assay design. We offer quality services, excellent customer support, and rapid turnaround time. Our design team is skilled in working with even the most...
Show the full description
EpigenDx is a genomic and epigenomic research company dedicated to providing superior products and laboratory services. Our technical expertise and focus on quality and rapid turnaround time have made us a dependable partner to our customers worldwide since 2006.
EpigenDx is the world-wide leading Pyrosequencing service provider in the biotechnology industry. Our lab has more than fifteen years of expertise in Pyrosequencing technology and assay design. We offer quality services, excellent customer support, and rapid turnaround time. Our design team is skilled in working with even the most difficult regions for epigenomic applications.
EpigenDx also specializes in targeted next-generation bisulfite sequencing (NGBS) services for affordable, fast, and precise sequencing of custom target regions. Our targeted bisulfite sequencing services can provide methylation data for more than dozens of genes and entire promoter regions in a single run. The researchers can choose from pre-existing panels or utilize our design services to develop a custom library covering your targets of interest. All of our off-the-shelf panels are validated with Pyrosequencing technology.
- Professional associations
- MassBio
- Website
- epigendx.com
Supplier diversity
SAM.gov small-business designations
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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