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Nano3D Biosciences (n3D)
Nano3D Biosciences (n3D) is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Magnetic 3D Bioprinting Fabricate spheroids representative of native cellular environments and easy to handle.
Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Disease Models
- Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Proliferation Measure cell number, cell viability and cell division.
In Vitro Pharmacology
- In Vitro Bone Models Measure osteoclast activity and bone formation in human or rat osteoclasts.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
In Vitro Toxicology
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cytotoxicity Test for effects on cell viability and proliferation
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
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Model Development
- Fresh Functional Human Tissue Contractile Force Assays Use fresh functional human tissue to assess contractile force with various compounds.
- Fresh Functional Human Tissue Vasoconstriction Assays Use fresh functional human tissue to assess vasoconstriction with various compounds.
- Fresh Functional Human Tissue Vasodilation Assays Use fresh functional human tissue to assess vasodilation with various compounds.
Oncology Models
- Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Testing Services
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Nano3D Biosciences, Inc. (n3D) operates in the general arena of cell culturing where we are both a contract service provider and manufacturer. Our mission is to develop the Bio-Assembler™ and the BiO Assay™ into the industry leading standard for 3-dimensional (3D), in vitro cell culturing and to apply this breakthrough technology in the fields of toxicology screening, drug discovery, and regenerative medicine. Our assay can also be used as a surrogate to the aortic ring assay. While other spheroid systems can mimic native cellular environments, they take a long time to form and are...
Show the full description
Nano3D Biosciences, Inc. (n3D) operates in the general arena of cell culturing where we are both a contract service provider and manufacturer. Our mission is to develop the Bio-Assembler™ and the BiO Assay™ into the industry leading standard for 3-dimensional (3D), in vitro cell culturing and to apply this breakthrough technology in the fields of toxicology screening, drug discovery, and regenerative medicine. Our assay can also be used as a surrogate to the aortic ring assay.
While other spheroid systems can mimic native cellular environments, they take a long time to form and are difficult to handle/retrieve. Magnetic 3D bioprinting addresses these issues by utilizing n3D’s core technology,magnetizing cells with NanoShuttle (NS) to print spheroids. Cells incubated with NS overnight are dispensed into an ultra-low attachment multiwell plate and printed into spheroids by placing the plate a top a drive of magnets (1 magnet/well). The magnets below the well will aggregate the cells using mild magnetic forces, printing a spheroid at the bottom of the well.
After only 15 min to a few hours, the plate of spheroids can be removed from the magnets and cultured long-term. Adding and removing solutions is made easy by the use of magnetic forces to hold down spheroids during aspiration, limiting spheroid loss. Spheroids can also be picked up and transferred between vessels using magnetic tools such as the MagPenTM.
Magnetic 3D bioprinting is a rapid and effective tool to print spheroids that are representative of native cellular environments and can be effectively used for high throughput toxicology screening.
+Downloads+
3D Bioprinting Presentation
- Website
- www.n3dbio.com
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