Biotranex

Biotranex LLC is a science-driven contract research laboratory. We are dedicated scientists with proven track records of success in drug discovery and development. We provide comprehensive solutions for ADME/PK, chemistry/lead optimization, and biomarker/structural biology issues. We do problem solvings for our clients to reduce the attrition rate of drug development. We deliver high quality services in a timely fashion.

ADME/PK Service Overview

Our services cover a broad spectrum of ADME, pharmacokinetic and toxicity studies. We tailor our capabilities to meet client’s needs. We partner with clients to address DMPK/toxicity issues, and to develop strategies to reduce attrition rate. We commit ourselves to offer the best services for our clients.

Service list:

• Absorption and Transporters
• Drug Metabolism/Chemical Toxicology
• Drug-Drug Interactions
• PK/PD
• Integrated DMPK Studies
• Integrated Drug Discovery Services
• Bioreactor/Metabolite Synthesis
• Analytical Supports
• Analysis of Biologics
• Consulting on IND/NDA Filings

Biology Service Overview

• Biomarker development
• Stable transfected cell lines
• Biological assay development
• Protein expression and purification
• Protein crystallography
• Structure-based drug design
• Fragment-based drug design

Chemistry Service Overview

• Hit-to-lead SAR exploration
• Lead optimization
• Custom synthesis of reference compounds and advanced intermediates
• Synthesis of metabolites
• Synthesis of deuterium labeled internal standards
• Synthesis of intermediates for preparation of radioactive compounds