OTC Biotech

OTC Biotech is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1

Countries 1

Type of company: Small business

Bioimaging

Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.

Chemical and Compound Analysis

Light Sheet Fluorescence Microscopy Use a planar sheet of light to section transparent tissues and generate a 3D image.

DNA & RNA

DNA-lipid interaction analysis Investigate cellular dynamics based on changes in fluorescent properties.
In Situ Hybridization Localize specific nucleic acid targets using labeled complementary probes.

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.

In Vitro Assays

Assay Development Construct or create new assays or modify existing ones.
Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Microbiology Study microbes and their role in human health.

In Vitro Pharmacology

Aptamer Products Obtain pre-made aptamers for specific target binding.
Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
SELEX Select and identify highly specific aptamers with binding affinities comparable to traditional antibodies.

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Product Orders

Kits and Reagents Submit a request to multiple vendors for kits and reagents.

United States San Antonio 1 site

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In the Fall of 2002, Operational Technologies Corporation’s (OpTech) managerial staff met to discuss establishing a biotechnology division. As part of these discussions, John G. Bruno, PhD, proposed to leverage the Small Business Innovation Research (SBIR) process to obtain government funding for aptamer research in the proposed division. OpTech concurred with this strategy and established a biotechnology division naming Dr. Bruno as the division’s Senior Scientist/Chief Technology Officer (CTO).
Using the SBIR process, proposals exploring the use of aptamers in both diagnostic and therapeutic arenas were submitted to government agencies. In 2003, the first SBIR award was received from the National Science Foundation along with four additional SBIR awards from other government sources. In April of 2004, OTC Biotechnologies (OTC BioTech) was created as a fully-owned OpTech subsidiary and R&D center to conduct biotechnology research using aptamers.
Dr. Bruno receives 2011 Tibbetts Award in Washington, DC on behalf of Operational Technologies Corp. Biotechnology Division or OTC BioTech
OTC Biotech’s aptamer research and development was recognized recognized by selection as one of the winners of the 2011 Tibbetts Award in recognition of SBA unique contributions as a model of excellence for the SBIR Program. Companies selected for this national award are recognized as having provided outstanding SBIR leadership.

Website: www.otcbiotech.com

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