Bioron Inc

Bioron Inc is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1

Countries 1

Type of company: New startup

Antibodies

Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.

Biomarkers

Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.

Chemical and Compound Analysis

Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.

Show all 9 in Chemical and Compound Analysis 3 more

Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.

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Chemistry, Manufacturing and Controls (CMC)

Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.

In Vitro ADME

Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.

In Vitro Assays

Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
HTS Assay Development Develop assays to use in high throughput screening.

In Vitro Pharmacology

High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Liposome Immunoassay Use immuno-liposomes for improved signal intensity and detection sensitivity compared to enzyme and fluorescent immunoassays.
Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.

In Vitro Toxicology

ADCC and CDC Assay Services Measure toxicity of antibodies.

Protein Sciences

Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
Fluorescence Polarization Investigate receptor-ligand interactions, protein-DNA interactions, proteolysis and membrane fluidity.
Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
Native Protein Purification Purify native proteins from sources such as tissue & serum.

Show all 15 in Protein Sciences 9 more

Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Protein mapping Interrogate the entire sequence of a protein.
Protein Purification Isolate native or recombinant proteins from a sample.
Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Yeast Two Hybrid Search novel interactions or confirm hypothesized protein-protein interactions using pairwise assays.

United States BOLINGBROOK 1 site

Bioron Inc. is a contract research organization providing a variety of services to facilitate the structure-based drug discovery process, including integrated gene-to-structure service, BioSAXS service and medicinal chemistry service. We are a team of highly skilled scientists with many years of expertise in biophysics and X-ray crystallography. We have access to the state-of-the-art laboratories for protein production, characterization and crystallization using highly automated robot systems. We have year-round access to several premier synchrotron facilities around the world to provide...

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Website: www.biorontech.com

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