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Celsion Labs

Celsion Labs is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Antibodies

  • Immunodetection Use antibodies to identify a protein or antigen.

Bioimaging

  • Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.

Biomarkers

  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • Interferon Gamma Release Assay Use in vivo or in vitro assays to measure the cell-mediated immune response to an infectious agent.

Cell Culture and Characterization

  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Cell Culture Culture primary or immortalized cell lines.
  • Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
  • Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
  • RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
  • Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Chemical and Compound Analysis

  • Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
  • UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.
Show all 51 services 38 more

Chemistry, Manufacturing and Controls (CMC)

  • Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.

Clinical Trials

  • Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.

Disease Models

  • Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
  • In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.

DNA & RNA

  • CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
  • DNA Extraction Extract DNA from an original source.
  • Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
  • PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
  • Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
  • qPCR Analysis Measure the accumulation of PCR products in real time.
Show all 9 in DNA & RNA 3 more
  • Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
  • RNA Extraction Isolate total RNA or mRNA from cells or tissues
  • RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.

General in vivo Toxicology

  • Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
  • Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

In Vitro Assays

  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.

In Vitro Toxicology

  • Cytotoxicity Test for effects on cell viability and proliferation

In Vivo Pharmacokinetics

  • In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
  • Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
  • Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
  • Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
  • Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
  • Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Model Development

  • Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
  • Zucker Rat Use a single animal species to create one or more disease models for cachexia.

Nanotechnology

  • Drug Delivery Technology Create microstructures that enhance drug metabolism properties.
  • Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.

Oncology Models

  • Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
  • Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
  • Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
  • Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Protein Sciences

  • Cytokines Find recombinant cytokines or cytokine assays.
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Huntsville 2 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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