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Ichor Life Sciences

Ichor Life Sciences is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

Agricultural Sciences Research & Development

Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties

Antibodies

Immunodetection Use antibodies to identify a protein or antigen.

Bioimaging

Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Mass Spectrometry Imaging Visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses
Medical Imaging Visualize and analyze internal structures in animal models or patients.
Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Scanning Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.

Biomarkers

Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.

Show all 12 in Biomarkers 6 more

Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.

Show all 132 services 118 more

Cell Culture and Characterization

Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
H & E Services For requesting services related to H&E Services
Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.

Chemical and Compound Analysis

Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Optical Tomographic Imaging Use multiply-scattered light to reconstruct images of illuminated objects.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.

Show all 8 in Chemical and Compound Analysis 2 more

Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Chemistry, Manufacturing and Controls (CMC)

Crystallization studies Crystallization studies

Clinical Consulting

Clinical Protocol Design & Development Creation of clinical protocol document which details how a clinical trial is designed, relating to to the methodology, hypothesis, and operation of clinical trial to ensure the safety of the patients is...
Clinical Study Reporting (CSR) Report results of clinical trials to regulatory agencies. This includes participant flow, baseline characteristics, outcome measures, statistical analyses, and adverse events.

Clinical Trials

Case Report Monitoring & Auditing Ensure the adequate collection and traceability of clinical data in preparation for review by the FDA.
Clinical Trial Design Develop study-related protocols, case report forms (CRFs) and database tools for records management.
Patient Recruitment Recruit and retain patients for clinical trials.
Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Site Monitoring Maintain oversight over participant's health during a clinical trial.
Site Selection Select clinical trial sites with clinicians who recruit, enroll, treat and evaluate trial patients.

Discovery Chemistry

LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.

Disease Models

Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
Macular Degeneration Models Use a single animal species to create one or more models for eye disease.

Show all 11 in Disease Models 5 more

Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
Obese Primates Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.

DNA & RNA

Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.

General in vivo Toxicology

Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
Dose Range Finding Study - Other Species Conduct a study to determine the dose range of your compound in other species.
Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

In Vitro ADME

Cell Fractionation Isolate organelles and subcellular components.

In Vitro Assays

3Screen™ 3D In Vitro Services 3Screen™ Platform enables complete 3D cell culture characterization.
Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Apoptotic Cell Staining Detect apoptotic cells in culture.
Assay Development Construct or create new assays or modify existing ones.
Cell Painting Cell painting is multiplexed image-based assay used to investigate subtle changes in cellular homeostasis
Cell Proliferation Measure cell number, cell viability and cell division.

Show all 10 in In Vitro Assays 4 more

In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.

In Vitro Pharmacology

Cellular Thermal Shift Assay Use a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
In Vitro Oncology Models Use cell-based and biochemical models of cancer.
Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Target Identification Identify the target(s) of a biologically active substance.

Show all 7 in In Vitro Pharmacology 1 more

Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

In Vitro Toxicology

ADCC and CDC Assay Services Measure toxicity of antibodies.
Cytotoxicity Test for effects on cell viability and proliferation
Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.

In Vivo Pharmacokinetics

In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
Ocular Pharmacokinetic (PK) Screening - Rabbit Conduct a pharmacokinetic screening study in rabbits that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Rat Conduct a pharmacokinetic screening study in rats that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.

Show all 7 in In Vivo Pharmacokinetics 1 more

Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.

Medical Communications

Pharmacodynamic/ Pharmacokinetic Reports Create Pharmacodynamic/ Pharmacokinetic reports to report to the appropriate regulatory bodies.

Model Development

Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.

Oncology Models

Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Pharmacology

In Vivo Pharmacology Study the effects of drug candidates in animal models

Protein Sciences

Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
Cytokines Find recombinant cytokines or cytokine assays.
ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Fluorescence Polarization Investigate receptor-ligand interactions, protein-DNA interactions, proteolysis and membrane fluidity.

Show all 22 in Protein Sciences 16 more

Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Lentivirus Production Develop lentiviruses and production protocols.
Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
NMR Determine molecular and protein structure, and validate sample integrity.
Protein Binding Determine drug-protein binding interactions
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
Quantitative MS Quantify small and large molecules in the pg/ml range
Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.

Specialty Dosing Routes

Intravitreal Toxicity and/or Toxicokinetic Study - Minipig Conduct an intravitreal ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Topical Dermal Toxicity and/or Toxicokinetic Study - Minipig Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to minipigs.
Topical Ocular Toxicity and/or Toxicokinetic Study - Mouse Conduct a topical ocular toxicity study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct a topical ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct a topical ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.

Show all 7 in Specialty Dosing Routes 1 more

Topical Ocular Toxicity and/or Toxicokinetic Study - Rat Conduct a topical ocular toxicity study in rats to determine the toxicity and toxicokinetic behavior of your compound.

Other services

New Request

United States LaFayette, SYRACUSE 2 sites

Woodland BioSciences is a preclinical contract research organization (CRO) providing innovative and customized solutions and consultation to the biotechnology community.
Our mission is to enhance drug development for the most severe cancers, inflammation and other major diseases.

We also enter shared-risk ventures through our bioincubator to help advance early molecules to value creation milestones.
Woodland BioSciences is a partnership and alliance between Woodland Pharmaceuticals and SBH Sciences.

Website: ichorlifesciences.com

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