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Luceome Biotechnologies
Luceome Biotechnologies is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Discovery Chemistry
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
In Vitro Assays
- Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- HTS Assay Development Develop assays to use in high throughput screening.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
In Vitro Pharmacology
- Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
- B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Human BCL Assays Use biochemical, cell-based or in vivo assays to measure BCL activity.
Show all 19 in In Vitro Pharmacology
- Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
- Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
- Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
- Mitogen/Extracellular signal-regulated Kinase (MEK) Assays Use biochemical, cell based or in vivo assays to measure MEK enzyme activity.
- Mutant B-Raf Assays Use biochemical, cell based or in vivo assays to measure mutant B-Raf enzyme activity.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
- Protein Kinase B (Akt) Assays Use biochemical, cell based or in vivo assays to measure Akt enzyme activity.
- Protein/Enzyme Targets For requesting Protein/Enzyme Targets
- Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
- Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
- Target Characterization Characterize potential drug targets during the drug discovery process.
- Target Identification Identify the target(s) of a biologically active substance.
- Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.
Show all 28 services
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Luceome's KinaseSeeker™ service utilizes a luminescence-based method for low-cost screening and profiling of potential drug candidates against a panel of kinases, in a near cellular environment. The resulting detection is sensitive with low background interference, allowing identification of target and off-target effects of drug candidates and minimizing background interference and hence false positives from test compounds. Features and Benefits • Luminescence detection: Low false positives from fluorescent compounds • Sensitive: Low Background; Broad dynamic range • Binding Assay: Identify...
Show the full description
Luceome's KinaseSeeker™ service utilizes a luminescence-based method for low-cost screening and profiling of potential drug candidates against a panel of kinases, in a near cellular environment. The resulting detection is sensitive with low background interference, allowing identification of target and off-target effects of drug candidates and minimizing background interference and hence false positives from test compounds.
Features and Benefits
• Luminescence detection: Low false positives from fluorescent compounds
• Sensitive: Low Background; Broad dynamic range
• Binding Assay: Identify active site directed and allosteric inhibitors
• Homogeneous: Portable; Adaptable to high-throughput
• Economical: 50 kinase panel profiling - $595 (Volume Discounts Available)
• Choose the kinases you want
• Rapid turnaround of data: 7 - 10 business days
• Data kept confidential
Services Offered
• Inhibition at single inhibitor concentrations
• Dose response titrations - IC50 determination
• Compound library screening
• Custom assay development
Available Panels for Profiling
• Panel 1: TK-rich (50 kinases, primarily TK/TKL family) - $595
• Panel 2: AGC-rich (50 kinases, primarily AGC family) - $595
• Panel 3: Mixed panel (50 kinases, representing all families) - $595
• Panel 4: Complete panel of 213 kinases - $2300
• A la Carte: $13.50/kinase/compound (Minimum order of $500 required)
Luceome provides a custom assay development service to clients who wish to use the luciferase fragment complementation assay for screening inhibitors in-house. We will tailor the assay to fit your profiling needs.
- Website
- www.luceome.com
Supplier diversity
SAM.gov small-business designations
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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