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EM Analytical Ltd

EM Analytical Ltd is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Bioimaging

  • Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
  • Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.
  • Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
  • Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
  • Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.

Cell Culture and Characterization

  • 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Bacterial Cell Culture Culture and Grow bacterial cells.
  • Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
  • Cell Culture Culture primary or immortalized cell lines.
  • Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Show all 10 in Cell Culture and Characterization 4 more
  • Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
  • Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
  • Resin-based Histology Perform sectioning and histological analysis of epoxy/acrylic/polycarbonate-embedded samples.
  • Yeast Cell Culture Grow yeast strains or species.
Show all 61 services 46 more

Chemical and Compound Analysis

  • Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
  • Atomic Force Microscopy Use atomic force microscopy to reveal information about the atomic topography and mechanical properties of a sample.
  • Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
  • Electron Diffraction Measurement (microED) Use electron diffraction patterns to characterize the crystallographic properties of a sample.
  • Energy Dispersive X-ray Spectroscopy Identify and estimate the elemental composition of a sample based on x-ray emission patterns.
  • Focused Ion Beam Apply a highly focused beam of gallium ions to remove material at high spatial resolution.
Show all 13 in Chemical and Compound Analysis 7 more
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
  • Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
  • Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
  • Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
  • Scanning and Transmission Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
  • UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

Discovery Chemistry

  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

DNA & RNA

  • DNA Sequencing Determine the nucleotide sequence of DNA samples.
  • qPCR Analysis Measure the accumulation of PCR products in real time.
  • Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
  • RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
  • Targeted Sequencing/Resequencing Detect variations in a genome subset.
  • Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.
Show all 7 in DNA & RNA 1 more
  • Whole Genome Sequencing Determine the entire genetic make-up of an organism.

Drug Development

  • Pharmacogenetics Consulting Access genomic services required for clinical trials, such as genotyping, genetic variation testing and DNA isolation.

In Vitro ADME

  • Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.

In Vitro Assays

  • 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • Fully Automated Assays Develop and perform assays that require no manual steps
  • Microbiology Study microbes and their role in human health.
Show all 10 in In Vitro Assays 4 more
  • Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
  • Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
  • Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Toxicology

  • Cytotoxicity Test for effects on cell viability and proliferation
  • Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
  • Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.

Nanotechnology

  • Nanofabrication Enable the construction of functional structures with nanoscale dimensions.
  • Nanofabrication Deposition and Growth Selectively accumulate ultra-thin films with desired physical properties.

Protein Sciences

  • X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.

Scientific Data Services

  • Pharmaco-genomics Genetic polymorphism contribution to inter-individual variability in drugs' responses and/or adverse events.

Testing Services

  • Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.

Other services

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Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Adlington 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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