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NJ Bio
NJ Bio is listed as a mid sized business research supplier in the Scientist.com network, with 3 sites in 1 country.
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3
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1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Agricultural Sciences Research & Development
- Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties
Antibodies
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
- Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- In-vivo Fluorescence In-vivo fluorescence enables visualisation and the study of biological processes in live organisms by using fluorescent markers.
- Mass Spectrometry Imaging Visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses
Biomarkers
- Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Peptide Bioanalysis Analyze the structure of Peptides.
- Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
- Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 127 services
Chemical and Compound Analysis
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- Chemical Stability Measure the stability of small molecules in solution.
- Chiral Separation Purify therapeutically active isomers of drug candidates.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Gas Chromatography Gas chromatography is an analytical technique that separates, identifies, and quantifies compounds in a mixture
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Show all 24 in Chemical and Compound Analysis
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Hydrophobic Interaction Chromatography Use a non-polar and non-denaturng mobile phase to separate components based on hydrophobicity.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Process Residual Impurities Detection Measure trace levels of impurities.
- Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
- Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.
- Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Show all 12 in Chemistry, Manufacturing and Controls (CMC)
- Compendial test methods Run Compendial test methods (e.g., KF)
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
- ICH-compliant stability testing Perform ICH-compliant stability testing
Clinical Trials
- BioAnalytical Laboratory Services Bioanalytical laboratory services provide essential testing to quantify drugs, metabolites, and biomarkers in biological samples (blood, urine, tissue) to support preclinical and clinical drug development
Discovery Chemistry
- Bio-Layer Interferometry Octet BLI is a label-free, real-time technology used to measure biomolecular interactions by detecting changes in optical interference patterns, offering insights into binding kinetics, affinity, and concentration.
- Bioanalytical Lab Services Bioanalytical Lab Services
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Show all 13 in Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Disease Models
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
DNA & RNA
- mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
- Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
General in vivo Toxicology
- Carcinogenicity Study - Mouse Conduct a repeat dose, chronic carcinogenicity study in mice to determine the tendency of your compound to produce tumors.
- Carcinogenicity Study - Rat Conduct a repeat dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
- Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
- Effective Dose (ED), 50% Toxicity Test Quantify the diluted toxin needed to induce sub-lethal effects upon constant exposure in half of test organisms.
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Show all 12 in General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
- Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
- Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.
- Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
- Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Human Biological Samples
- Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...
In Vitro ADME
- Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
- Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
- Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
Show all 10 in In Vitro ADME
- Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
- Non Isotopic Labeling Track unlabeled macromolecules through a metabolic pathway or cell.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
- Reference Standards Find reference standards for assays, tests and services.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Assay Development Construct or create new assays or modify existing ones.
- Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
In Vitro Pharmacology
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
In Vivo ADME
- Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Integrated In Vivo Services Package Process an entire In Vivo Project including: Dose Formulation, PK Screening, ADME-Profiling, Toxicology, Safety Pharmacology, DART, IND Filing from our bundle of suppliers.
- Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
- Mouse Efficacy Monotherapy Use mouse models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Show all 9 in In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
- Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
- Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
Oncology Models
- Ex-Vivo PDX Screening Ex-vivo PDX screening is used to evaluate the effectiveness of various drugs on tumor cells.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Pharmacology
- In Vivo Pharmacology Study the effects of drug candidates in animal models
Protein Sciences
- Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
- LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
- NMR Determine molecular and protein structure, and validate sample integrity.
- PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
- Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
- Protein Binding Determine drug-protein binding interactions
Show all 10 in Protein Sciences
- Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
- Protein Labeling Find suppliers who offer attaching detectable tags like fluorophores or enzymes to proteins
- Protein Sequencing Determine the amino acid sequence of protein or peptide.
- Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.
REACH Services
- In Vivo REACH Services Performing testing when in vitro studies cannot be used to predict biological responses
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Elevated Temperature Stability Determine the stability of a product at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Website
- www.njbio.com
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
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