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Lonza Early Development Services
Lonza Early Development Services is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.
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Logo Unknown author Unknown author, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
- Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
- In Silico Humanization Predict epitope binding specificity, increase in vivo half-life and allow rapid modeling and humanization of antibodies.
Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Interferon Gamma Release Assay Use in vivo or in vitro assays to measure the cell-mediated immune response to an infectious agent.
Show all 7 in Biomarkers
- T Cell Epitope Characterization Evaluate the potency and immunodominance of T-cell epitopes within a molecule.
Cell Culture and Characterization
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
Chemical and Compound Analysis
- Photostability Measure drug degradation rates after exposure to various light sources.
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 39 services
Data Science/Bioinformatics
- In Silico Protein Modification Analysis Use computational methods to predict the behavior of modified proteins.
DNA & RNA
- RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Human Biological Samples
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Cell Lysates For requesting human Cell lysates.
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- ELISpot Assay and Testing Detect low levels of antigens.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
Show all 7 in In Vitro Assays
- In Vitro Human Cell Assays Request in vitro human cells for assays
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- MAPPs (MHC-II-associated peptide proteomics) MAPPs, or MHC-II-associated peptide proteomics, is a mass spectrometry technique for identifying peptides from therapeutic proteins that are presented by MHC class II molecules on antigen-presenting cells.
- Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
- Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
Safety Pharmacology
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
Other services
- Human Dendritic Cell (hDC) Model Test and validate the immune-modulating compounds in DC immune pathway models.
- New Request
- Website
- www.lonza.com/biologics
Where it operates
Sites by country, with the cities in each.
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United Kingdom 1 site
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