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Genesis Drug Discovery & Development
Genesis Drug Discovery & Development is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
Bioimaging
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Biomarkers
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Chemical and Compound Analysis
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Structural Chemistry Examine the relationship between protein structure and function.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Discovery Chemistry
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
Disease Models
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
- Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
Show all 8 in Disease Models
- Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
- Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
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Human Biological Samples
- Custom PDX models For requesting Custom PDX models
- Existing PDX models For requesting Existing PDX models
In Vitro ADME
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
- Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Ocular Permeability Measure passive diffusion and active transport of drugs across confluent ocular epithelial cells.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
In Vitro Assays
- Microbiology Study microbes and their role in human health.
In Vitro Pharmacology
- HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
In Vivo ADME
- Ocular Distribution Study - Other Species Conduct a study to determine the distribution of your compound in ocular tissues of other species.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Medical Communications
- Medical Writing and Editing/Manuscript Development Communicate scientific, technical and health-related information to a range of audiences.
Oncology Models
- Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Oncology Xenografts Xenografts derived from oncological samples.
- Oral Xenograft Measure therapeutic endpoints in oral cancer models as well as cancer models related to the Pharynx.
- Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
- Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
Show all 8 in Oncology Models
- Urinary System Xenografts Xenografts derived from organs of the Urinary system. This includes, but is not limited to, xenografts from the Bladder, Kidney, and Urethra.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
- Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Other services
- New Request
- Website
- www.gd3services.com
Where it operates
Sites by country, with the cities in each.
-
United States 1 site
Supplier diversity
SAM.gov small-business designations
Minority-owned
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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