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NemaLife Inc

NemaLife Inc is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Bioimaging

  • Fluorescence-Lifetime Imaging Microscopy (FLIM) Use FLIM to produce an image based on the differences in the excited state decay rate from a fluorescent sample.
  • In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
  • In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.

Biomarkers

  • Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
  • Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.

Chemical and Compound Analysis

  • Fluorescence Mediated Tomography Visualize the spatial distribution of fluorescencently labeled probes and substances.

Chemistry, Manufacturing and Controls (CMC)

  • Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.

Developmental and Reproductive Toxicology (DART)

  • Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Disease Models

  • Excitotoxicity Models Measure therapeutic endpoints in animal models with excitotoxic pathology.
  • Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
  • In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
  • Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
  • Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
Show all 42 services 26 more

DNA & RNA

  • RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
  • RNAi Pathway Analysis Use high-throughput RNAi genetic screens to elucidate relevant signaling pathways.

Effectiveness

  • Field Dose Confirmation Studies Conduct an in vivo study to confirm the effectiveness of a selected drug dose in actual field conditions.
  • Laboratory Dose Confirmation Studies Conduct in vivo studies to confirm the effectiveness of a selected drug dose in the lab.
  • Laboratory Dose Determination Studies Compare the effectiveness of three non-zero therapeutic concentrations for various durations to a non-medicated control group, and a non-medicated uninfected control group.

General in vivo Toxicology

  • Dose Range Finding Study - Other Species Conduct a study to determine the dose range of your compound in other species.
  • Effective Dose (ED), 50% Toxicity Test Quantify the diluted toxin needed to induce sub-lethal effects upon constant exposure in half of test organisms.
  • General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
  • Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.

In Vitro Assays

  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.

In Vitro Pharmacology

  • Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

In Vitro Toxicology

  • Cytotoxicity Test for effects on cell viability and proliferation
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.

Model Development

  • Transgenic Models Create animal models engineered for use in a specific therapeutic area.

Neurotoxicology

  • Single Dose Acute Neurotoxicity Study - Other Species Conduct a single dose study in other species to determine the neurotoxicty of your compound.

Oncology Models

  • Muscle Wasting Models Measure therapeutic endpoints in animal models of muscle wasting.

REACH Services

  • OECD 414: Prenatal Developmental Toxicity Study This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism.
  • OECD 416: Two-Generation Reproduction Toxicity This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive...
  • OECD 421: Reproduction/Developmental Toxicity Screening Test The test substance is administered in graduated doses to several groups of males and females.
  • OECD 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance.
  • OECD 451: Carcinogenicity Studies The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test...
  • OECD 452: Chronic Toxicity Studies Evaluate the direct and indirect impact of prolonged and repeated toxin exposure to test organisms.

Safety Pharmacology

  • Repeat Dose Neurotoxicity Study - Other Species Conduct a repeat dose study in other species to determine the neurotoxicity of your compound.

Specialty Dosing Routes

  • Lethal Dose (LD), 50% Toxicity Test Measure acute toxicity by identifying the amount of pure toxin required to kill half of the experimental subjects.
  • Single Dose Acute Inhalation Study - Other Species Conduct a single dose inhalation study in other species to determine the toxicokinetic behavior of your compound.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Lubbock 2 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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