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MetabAxis Laboratories
MetabAxis Laboratories is listed as a research supplier in the Scientist.com network, with 3 sites in 1 country.
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Sites
3
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
Cell Culture and Characterization
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Chemical and Compound Testing
- Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.
Clinical Consulting
- Study Budgeting Consulting Request for Consulting Services
Disease Models
- Acute Liver Failure Models Measure therapeutic endpoints in animal models of acute liver failure.
- Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
- Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
- In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
Show all 12 in Disease Models
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
- Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
- Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
- Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
- Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
Food Safety & Regulations
- Carbohydrate Testing Determine the types and concentrations of carbohydrates in foods for nutritional labeling, quality control, and for identifying possible adulteration.
General in vivo Toxicology
- Carcinogenicity Study - Mouse Conduct a repeat dose, chronic carcinogenicity study in mice to determine the tendency of your compound to produce tumors.
- Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
- Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Show all 42 services
In Vitro ADME
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
In Vitro Pharmacology
- In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
In Vitro Toxicology
- Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Oncology Models
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
REACH Services
- OECD 407: Repeated Dose 28-day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.
- OECD 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.
- OECD 410: Repeated Dose Dermal Toxicity: 21/28-day Study This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance.
- OECD 414: Prenatal Developmental Toxicity Study This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism.
- OECD 416: Two-Generation Reproduction Toxicity This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive...
- OECD 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance.
Show all 8 in REACH Services
- OECD 423: Acute Oral toxicity - Acute Toxic Class Method The acute toxic class method set out in this Guideline is a stepwise procedure with the use of 3 animals of a single sex per step. Depending on the mortality and/or the moribund status of the animals, on average 2-4...
- OECD 451: Carcinogenicity Studies The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test...
Safety Pharmacology
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Target Animal and Human Food Safety
- Toxicity Test for Veterinary Drugs Use the drug at 10X the recommended dose for 3X the recommended duration to evaluate its safety.
- Website
- www.metabaxis.com
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
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