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ION Biosciences

ION Biosciences is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Bioimaging

  • Fluorescence-Lifetime Imaging Microscopy (FLIM) Use FLIM to produce an image based on the differences in the excited state decay rate from a fluorescent sample.
  • Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.

Cell Culture and Characterization

  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Discovery Chemistry

  • Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.

In Vitro Assays

  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • Assay Development Construct or create new assays or modify existing ones.
  • Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
Show all 7 in In Vitro Assays 1 more
  • HTS Assay Development Develop assays to use in high throughput screening.

In Vitro Pharmacology

  • Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
  • Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
  • Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
Show all 10 in In Vitro Pharmacology 4 more
  • Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.
  • Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
  • Solute-Linked Carrier (SLC) Transporter Inhibition Assays Use biochemical, cell-based or in vivo assays to measure solute-linked carrier transporter activity.
  • Solute-Linked Carrier (SLC) Transporter Substrate Identification Use biochemical, cell-based or in vivo assays to identify solute-linked carrier transporter substrates.
Show all 30 services 13 more

In Vitro Toxicology

  • Cardiac Channels Measure the arrhythmia producing potential of test compounds.
  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Cytotoxicity Test for effects on cell viability and proliferation
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.

Protein Sciences

  • Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
  • Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
  • Protein Labeling Find suppliers who offer attaching detectable tags like fluorophores or enzymes to proteins

Other services

  • Qube - High Throughput Screening Screen large compound libraries for ion channel blockers and modulators.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States San Marcos 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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