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Sapient

Sapient is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
  • Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
  • Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Show all 15 in Biomarkers 9 more
  • Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
  • Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
  • Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
  • Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
  • Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
  • Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
  • Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
  • Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.

Cell Culture and Characterization

  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Chemical and Compound Analysis

  • GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • Sample Bioanalysis Determination of concentration of an analyte in biological sample.

Data Science/Bioinformatics

  • Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
  • Clinical Companion Diagnostics Analysis The process of finding patients who are likely to respond positively to a drug and designing a diagnostic tool to identify this group of patients before or with a therapy.
  • Clinical Data Analysis Analysis that helps you make sense of your clinical data
  • Clinical Responder Analysis, Patient Stratification The process of identifying patients that are more likely to respond positively to a drug.
  • Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
Show all 44 services 29 more

Discovery Chemistry

  • Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.

General in vivo Toxicology

  • General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

In Vitro ADME

  • Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
  • Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.

In Vitro Assays

  • Assay Development Construct or create new assays or modify existing ones.
  • Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.

In Vitro Toxicology

  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.

Protein Sciences

  • Cytokines Find recombinant cytokines or cytokine assays.
  • Integrated Proteomics Package Process an entire Proteomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers
  • LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
  • Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
  • Protein Identification Uncover or confirm the identity of a protein.
  • Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Show all 8 in Protein Sciences 2 more
  • Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
  • Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.

Safety Pharmacology

  • Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.

Scientific Data Services

  • Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
  • Metabolomics Data Analysis Use metabolites to identify any potential biomarkers or novel therapeutic targets that may play a role in the mechanisms responsible for the progression of a disease.

Other services

  • New Request  

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States San Diego 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Professional associations
AAPS, BIOCOM
Website
www.sapient.bio

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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