- Supplier site
- Group of sites (click to zoom)
Scientist.com supplier network (site locations)
Research supplier
K2 Biolabs, LLC
K2 Biolabs, LLC is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
View K2 Biolabs, LLC on Scientist.com
Email me this page as a PDF
Sign in to Scientist.com to open this supplier in your organization's marketplace.
Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
- Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
- Cell Line Construction Create new recombinant cell lines to exact specifications.
Show all 19 in Cell Culture and Characterization
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
- Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
- Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
- Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
- Single Cell DNA Sequencing Examine genetic variations in a single cell.
- Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
- Spent Media Analysis Measure chemical alterations, such as variations in amino acids, glucose, contaminants, and metabolites, in a cell culture medium throughout the culturing process.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
- Stem Cell Methodologies Study Stem Cell characteristics.
Show all 90 services
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- IND Enabling Package Request a package of Investigational New Drug (IND) Enabling Studies from our group of trusted suppliers that have enrolled in our IND-Enabling Package Program.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
Disease Models
- Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
- In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
- Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
- Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
- Malaria Models Measure therapeutic endpoints in animal models of malaria.
- Tissue Rejection Models Measure therapeutic endpoints in animal models of tissue rejection.
DNA & RNA
- ddPCR-Based Plasma Genotyping Perform noninvasive tumor genotyping.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
Drug Development
- Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
Effectiveness
- In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
In Vitro ADME
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Show all 9 in In Vitro Assays
- In Vitro Human Cell Assays Request in vitro human cells for assays
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
In Vitro Pharmacology
- HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Integrated In Vivo Services Package Process an entire In Vivo Project including: Dose Formulation, PK Screening, ADME-Profiling, Toxicology, Safety Pharmacology, DART, IND Filing from our bundle of suppliers.
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Model Development
- Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
- Pseudopregnant CD1 Mouse Use a single animal species to create gene-modified mouse models.
- SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
- SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
Oncology Models
- Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
- Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
- NCG Model Study tumor biology and immuno-oncology in the CRISPR/Cas9-generated immunodeficient mouse model.
- Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Oncology Xenografts Xenografts derived from oncological samples.
REACH Services
- In Vitro REACH Services Perform skin or eye irriation tests, sensitivily and geneotoxicity tests
- In Vivo REACH Services Performing testing when in vitro studies cannot be used to predict biological responses
Safety Pharmacology
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
Testing Services
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
Other services
- In Vitro Neurodegenerative Disease Platform Use an IVND platform to screen different compounds/drugs in a finely controlled synaptopathies scenario.
- Website
- www.k2-biolabs.com
Where it operates
Sites by country, with the cities in each.
-
United States 1 site
Supplier diversity
SAM.gov small-business designations
Minority-owned
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
Work with K2 Biolabs, LLC on Scientist.com
For prices, more details, or to contact K2 Biolabs, LLC, visit Scientist.com.
Sign in to Scientist.com to open this supplier in your organization's marketplace.