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GemPharmatech LLC (North American Orders)

GemPharmatech LLC (North American Orders) is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Antibodies

  • Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.

Bioimaging

  • In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
  • Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.

Disease Models

  • Acute Kidney Failure Models Measure therapeutic endpoints in animal models of acute kidney failure.
  • Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
  • Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
  • Auto-immune Hepatitis Models Measure therapeutic endpoints in animal models with auto-immune hepatitis.
  • Autoimmune Models Measure therapeutic endpoints in animal models with autoimmune disorders.
  • Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
Show all 50 in Disease Models 44 more
  • Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
  • Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
  • Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
  • Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
  • Cognition Models Measure therapeutic endpoints in animal models of cognition.
  • Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
  • Cyp2f2 Knockout Mouse Study Cyp2f2-mediated lung metabolism.
  • Demyelination Models Measure therapeutic endpoints in animal models with demyelination pathology.
  • Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
  • Excitotoxicity Models Measure therapeutic endpoints in animal models with excitotoxic pathology.
  • Fecal Microbiota Transplantation (FMT) - Mouse Use germ-free mice to evaluate the properties of complex or defined gut microbiota following fecal microbiota transplantation (FMT). Axenic (germ-free) mice transplanted with donor microbiota can be utilized to assess...
  • General Pain Models Measure therapeutic endpoints in animal models of general pain.
  • Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
  • IGA Glomerulonephritis Models Measure therapeutic endpoints in animal models of IgA glomerulonephritis.
  • In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
  • Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
  • Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
  • Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
  • Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
  • Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
  • Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
  • Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
  • Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
  • Morris Water Maze Investigate spatial learning and memory in rodents.
  • Myelination Models Measure therapeutic endpoints in animal models with induced myelination, remyelination or developmental myelination.
  • Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
  • Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
  • Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
  • Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
  • Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
  • Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
  • Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
  • Osteoporosis Models Measure therapeutic endpoints in animal models of osteoporosis.
  • Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
  • Pain Models Test therapeutic efficacy of drug candidate in pain model.
  • Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
  • Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
  • Receptor Occupancy Models Determine the effective dose and concentration needed to reach effective levels in a given tissue.
  • Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
  • Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
  • Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.
  • Tissue Rejection Models Measure therapeutic endpoints in animal models of tissue rejection.
  • Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.
  • Xenografts Evaluate drug candidate in tissue graft or organ transplant model.

DNA & RNA

  • CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
  • Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
  • Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
Show all 102 services 90 more

Human Biological Samples

  • Custom PDX models For requesting Custom PDX models
  • Existing PDX models For requesting Existing PDX models

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.

In Vitro Pharmacology

  • In Vitro Excitotoxicity Models Use in vitro models to measure therapeutic endpoints associated with excitotoxic pathology.
  • In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
  • In Vitro Fertilization Models Measure oocyte maturation, embryo development in culture and sperm fertilizing ability.
  • In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.
  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.

In Vivo Pharmacokinetics

  • In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).

Model Development

  • Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
  • Custom Model Development Develop a custom disease model.
  • Disease Model Database For sourcing disease models.
  • Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
  • Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
  • PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
Show all 11 in Model Development 5 more
  • PiggyBac Transgenic Mouse Service Obtain single-copy transgenic embryos with consistent expression of any desired transgene.
  • SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
  • Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
  • Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
  • Transgenic Models Create animal models engineered for use in a specific therapeutic area.

Non-Human Biospecimen

  • Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
  • Rat Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.

Oncology Models

  • Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
  • Animal Hypoxia Models Measure therapeutic endpoints in hypoxic animal models.
  • Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
  • Digestive System PDX Patient derived xenografts relating to organs and components of the digestive system. This includes, but is not limited to the Stomach, Intestines, Liver, Colon, Colorectal samples and Gastric samples.
  • Endocrine System PDX Patient derived xenografts related to the endocrine system. PDX related to glands controlling hormone regulation such as the Pituitary glands, Thyroid Glands, Adrenals, and Pancreas.
  • Endocrine System Xenograft Xenografts derived from organs and glands of the Endocrine system. This include samples from the Pituitary Gland, Thyroid, and Adrenals.
Show all 20 in Oncology Models 14 more
  • Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
  • NCG Model Study tumor biology and immuno-oncology in the CRISPR/Cas9-generated immunodeficient mouse model.
  • Nervous System PDX Patient derived xenografts relating to the components of the Nervous System. This includes PDX from the Brain, Spinal Cord, and Nerves.
  • Nervous System Xenografts Xenografts relating to the Nervous system. This includes samples from the Head, Neck, Brain, and Nerves.
  • Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
  • Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
  • Oncology Xenografts Xenografts derived from oncological samples.
  • Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
  • Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
  • Reproductive System PDX Patient derived xenografts relating to reproductive systems. This includes PDX from reproductive organs such as the Ovaries, Cervix, Breasts, Testes, Prostate, and Scrotum.
  • Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
  • Urinary System PDX Patient Derived Xenografts relating to organs that comprise the Urinary system. This includes, but is not limited to, samples from the Kidneys, Liver, and Bladder.
  • Urinary System Xenografts Xenografts derived from organs of the Urinary system. This includes, but is not limited to, xenografts from the Bladder, Kidney, and Urethra.
  • Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Safety Pharmacology

  • CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
  • Self Administration Study - Rat Conduct a study to investigate the potential addictive characteristics of your compound in rats.

Specialty Dosing Routes

  • Intrathecal/Intraspinal Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the intrathecal space.

Other services

  • New Request  

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States San Diego 2 sites

Source: Scientist.com supplier network (site locations)

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