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Gnome Diagnostics, LLC

Gnome Diagnostics, LLC is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
  • Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
  • Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
  • Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Show all 23 in Biomarkers 17 more
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
  • Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
  • Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
  • Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
  • Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
  • Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
  • Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • Microfluidics-Based Biomarker Isolation and Detection Isolate and detect rare biomarkers in blood samples, such as CTCs, cfDNA, and exosomes.
  • Multiplex Circulating miRNA Assay Profile miRNAs directly from just 10 μl of crude biofluid or 0.1 ng of purified RNA.
  • Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
  • Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
  • Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
  • Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.

Cell Culture and Characterization

  • Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
  • H & E Services For requesting services related to H&E Services
  • Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
  • Resin-based Histology Perform sectioning and histological analysis of epoxy/acrylic/polycarbonate-embedded samples.
  • Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.

Clinical Consulting

  • Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Show all 47 services 35 more

Data Science/Bioinformatics

  • Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
  • Discovery Biomarker Analytics An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
  • Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.

DNA & RNA

  • Cell Free DNA Assay Detect known mutations and discover new ones in cell-free plasma DNA.
  • DNA Extraction Extract DNA from an original source.
  • DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
  • Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
  • Genotyping Examine a DNA sequence to identify specific genetic varients .
  • qPCR Analysis Measure the accumulation of PCR products in real time.
Show all 10 in DNA & RNA 4 more
  • RNA Extraction Isolate total RNA or mRNA from cells or tissues
  • RNAscope In Situ Assays Profile single-cell gene expression in situ.
  • Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
  • Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.

Drug Development

  • Pathophysiology Consulting Request services related to Pathophysiology Consulting

Human Biological Samples

  • Human TMA For requesting Human Tissue MicroArrays

In Vitro Assays

  • Human Custom TMA For requesting Human Custom Microarray Services

Scientific Data Services

  • Automated Image Analysis Automated Image Analysis
  • Small RNA Gene Expression Quantify and analyze miRNA, piRNA, siRNA as well as other small nuclear RNAs from small-RNA-seq raw input data sets.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Powell 2 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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