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PeploBio
PeploBio is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Biomarkers
- Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Construction Create new recombinant cell lines to exact specifications.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
- Clinical Study Reporting (CSR) Report results of clinical trials to regulatory agencies. This includes participant flow, baseline characteristics, outcome measures, statistical analyses, and adverse events.
- Clinical Trial Consulting Consulting services for Clinical trials.
- Clinical Trial Recruitment Recruitment, enrollment and retention of patients for clinical trials.
Show all 75 services
Clinical Trials
- Clinical Trial Design Develop study-related protocols, case report forms (CRFs) and database tools for records management.
- Clinical Trial Risk Management Plan that maintains treatment quality throughout lifecycle and improve decision making.
- Patient Recruitment Recruit and retain patients for clinical trials.
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- Clinical Companion Diagnostics Analysis The process of finding patients who are likely to respond positively to a drug and designing a diagnostic tool to identify this group of patients before or with a therapy.
Discovery Chemistry
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
DNA & RNA
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
- Cell Free DNA Assay Detect known mutations and discover new ones in cell-free plasma DNA.
- Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- DNA Extraction Extract DNA from an original source.
Show all 20 in DNA & RNA
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
- DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
- Exome Sequencing Determine protein-coding nucleotide sequences in a DNA sample.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
- Methylation Specific PCR Determine the methylation status of a CpG site without the need for base-specific endonucleases.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- Restriction Fragment Length Polymorphism Identification Uses gel electrophoresis to identify differences in restriction fragment lengths produced by enzymatic digestion of DNA.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
- RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
- RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
- Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
Drug Development
- Consulting Services Work with consultants who provide expert advice in various areas of research and technology.
Human Biological Samples
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
In Vitro ADME
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- Human Immuno-deficiency Virus Infection CDx Design and validate companion diagnostics for HIV infection that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Show all 8 in In Vitro Assays
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.
In Vitro Pharmacology
- Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
- B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
- Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Assays Use biochemical, cell based or in vivo assays to measure CTLA-4 receptor activity.
- Extracellular signal Regulated Kinase Assays Use biochemical, cell based or in vivo assays to measure ERK enzyme activity.
- Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
- HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
Show all 16 in In Vitro Pharmacology
- Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
- Mammalian Target of Rapamycin Complex Assays Use biochemical, cell based or in vivo assays to measure mTORC enzyme activity.
- Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
- Programmed Death-Ligand 2 (PD-L2) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of PD-L2 ligand.
- Protein Kinase B (Akt) Assays Use biochemical, cell based or in vivo assays to measure Akt enzyme activity.
- Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
- RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.
- Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Oncology Models
- CAR-T Efficacy In Vivo assessment of CAR-T and CAR-NK efficacy in a humanized mouse
Pharmacovigilance
- GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Scientific Data Services
- Epigenomics Data Analysis Quantify and analyze DNA methylation and/or DNA binding protein data sets.
- Pharmaco-genomics Genetic polymorphism contribution to inter-individual variability in drugs' responses and/or adverse events.
- Website
- www.peplobio.co.uk
Where it operates
Sites by country, with the cities in each.
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United Kingdom 2 sites
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