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Glint Lab

Glint Lab is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

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Type of company: New startup

Antibodies

Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse
Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.

Biomarkers

Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.

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Osteoclasts Measure osteoclast activity and bone resorption in human, mouse or rat assays.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Solid Tumor CDx Design and validate companion diagnostics for solid tumors that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
TUNEL Assay Detect in situ DNA fragmentation.

Cell Culture and Characterization

3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Microphysiological Systems/organoid transcriptomics Microphysiological Systems/organoid transcriptomics

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Data Science/Bioinformatics

Discovery Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.
Discovery Biomarker Analytics An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Discovery In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your Genomics/Transcriptomics data
Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Microarray Data Analysis Visualize and analyze microarray data and facilitate data analysis for large experiments.
Translational Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.

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Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Translational Data Analysis Analysis that helps you make sense of your translational data
Translational Data Science and Modeling A process that helps make sense of your translational data
Translational In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your omics data
Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.

Disease Models

Acute Kidney Failure Models Measure therapeutic endpoints in animal models of acute kidney failure.
Acute Lung Injury Models Measure therapeutic endpoints in animal models of acute lung injury.
Artery On-A-Chip Platform Assess small blood vessels under near-in vivo conditions.
Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Bone Models Measure therapeutic endpoints in animal models of bone disorders.
Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.

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Kidney Transplant Models Measure therapeutic endpoints in kidney transplant models.
Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.

DNA & RNA

HCR™ RNA-FISH Detect and visualize RNA expression in situ
Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
Spatial Transcriptomics Determine the sub-cellular localization of mRNA molecules. Use this to identify cellular heterogeneity in tissues, tumors, immune cells and the subcellular distribution of transcripts.

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Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Pathophysiology Consulting Request services related to Pathophysiology Consulting
Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.
Toxicology Consulting Use models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

Human Biological Samples

Custom FFPE cell line blocks Custom IHC compatible FFPE cell line blocks and sections
Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
Human TMA For requesting Human Tissue MicroArrays

In Vitro Assays

3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.

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Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Fully Automated Assays Develop and perform assays that require no manual steps
High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
HTS Assay Development Develop assays to use in high throughput screening.
Human Custom TMA For requesting Human Custom Microarray Services
Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
Immunofocus™ Predict the response to anti PD1/PDL1 directed therapies.
In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
Microbiology Study microbes and their role in human health.
Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
SARS-CoV-2 (COVID-19) Assays Search for Available SARS-CoV-2 Assays
Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
Von Willebrand Factor Analysis Detect and classify the Von Willebrand disease sub-type.

In Vitro Pharmacology

Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vitro Oncology Models Use cell-based and biochemical models of cancer.

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Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Target Characterization Characterize potential drug targets during the drug discovery process.
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.

In Vitro Toxicology

Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
Toxicology- in vitro Toxicity testing and model development in vitro on developmental and adult neurotoxicity
Zebrafish Embryo Toxicity Use a single animal species to create one models of toxicity.

Model Development

3D Blood-Brain Barrier Model Use an in vitro 3D blood–brain barrier model for real-time visualization of cellular and barrier functions.
Zebrafish Animal Model Model human disease and development in zebrafish.

Oncology Models

Animal Hypoxia Models Measure therapeutic endpoints in hypoxic animal models.
Ex-Vivo PDX Screening Ex-vivo PDX screening is used to evaluate the effectiveness of various drugs on tumor cells.
Immuno-PDX Utilize the patient-derived xenograft for drug response profiling and biomarker discovery of immuno-oncology drug candidates.
Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Protein Sciences

Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.

Scientific Data Services

Automated Image Analysis Automated Image Analysis
Foundation Model A foundation model is a large-scale AI model trained on extensive datasets, designed to be adaptable for a variety of specific tasks.
Marker Analyses Identify associations between genetic markers and traits of interest to determine markers responsible for human diseases.

Specialty Dosing Routes

Dermal Toxicology Assess toxicity in rodent dermal testing models.
Intravitreal Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct an intravitreal ocular toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Other Species Conduct an intravitreal ocular toxicity study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intravitreal ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.

Other services

New Request

United States San Diego 1 site

Professional associations: BIOCOM
Website: glintlab.com

Woman-owned Minority-owned

US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.

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