Macrocyclics, inc.

Macrocyclics, inc. is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1

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Type of company: Small business

Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.

Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
Chemical Stability Measure the stability of small molecules in solution.
Compound Integrity Analyze the identity and purity of small molecule drug candidates.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Liquid Chromatography Separate substances using a mobile and stationary phase.
Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.

Analytical Development and Validation Request services related to Analytical Development and Validation
API and Drug Product Stability Testing API and Drug Product Stability Testing.
API and drug product storage and release API and drug product storage and release
API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Show all 13 in Chemistry, Manufacturing and Controls (CMC) 7 more

Compendial test methods Run Compendial test methods (e.g., KF)
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
Fill and Finish Processing Confirm final product sterility, formulation and packaging in the biopharmaceutical process.
Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
ICH-compliant stability testing Perform ICH-compliant stability testing

Show all 34 services 20 more

Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Radiochemical Synthesis Radiolabel small molecules, peptides, cytotoxics or antibody drug conjugates for DMPK analysis.

Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.

Radiolabeled Tracers Use radiolabeled drug metabolites as radiotracers for measuring desired physiological processes.

Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.

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