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Protein Evolution
Protein Evolution is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Compliance and Quality Control Measures
- Residue Chemistry Pesticide residue and tolerance testing.
Antibodies
- Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
- Pepscan Analysis Screen overlapping peptide sequences to identify linear epitopes.
Biomarkers
- Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Peptide Bioanalysis Analyze the structure of Peptides.
- Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
Chemical and Compound Analysis
- Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Show all 13 in Chemical and Compound Analysis
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
- Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Structural Chemistry Examine the relationship between protein structure and function.
- Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.
- Viscosity Testing Evaluate the fluid flow properties of liquids for product evaluation and quality control.
Show all 66 services
Chemistry, Manufacturing and Controls (CMC)
- Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
- Integrated Antibody Development Package-UK Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Data Science/Bioinformatics
- Discovery Compound Screening Analytics Screening of an entire compound library directly against the drug target or in a more complex assay.
- Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
- Translational Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.
- Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Custom Libraries Find or synthesize mg to kg amounts of target-specific and target-agnostic compounds for HTS and biological profiling.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
DNA & RNA
- De Novo Genome Sequencing Determine the DNA sequence of uncharacterized genomes.
- DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
- DNA-lipid interaction analysis Investigate cellular dynamics based on changes in fluorescent properties.
- Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
Farm & Livestock Solutions
- Processing Techniques Investigation of mechanisms and kinetics of specific reactions for the improvement and stability of bioactive compounds.
In Vitro ADME
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
- Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
- Protein/Enzyme Targets For requesting Protein/Enzyme Targets
- Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
Protein Sciences
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
- Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
- NMR Determine molecular and protein structure, and validate sample integrity.
- Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Show all 18 in Protein Sciences
- Phage Display Use in vitro screening method to identify protein binding partners.
- Protein Binding Determine drug-protein binding interactions
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Identification Uncover or confirm the identity of a protein.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein mapping Interrogate the entire sequence of a protein.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Sequencing Determine the amino acid sequence of protein or peptide.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
- X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Raw Materials
- Weight Control Active Ingredients Acquire weight control active ingredients active ingredients for making over-the-counter medicines.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Large Language Models Use of Large Language models in target discovery, clinical trial design and development, analysis of clinical trial data and regulatory submissions. Services are tailored to the problem, specific context of biopharma.
- Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
- Website
- pei.bio
Where it operates
Sites by country, with the cities in each.
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United States 1 site
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