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Metrion Biosciences

Metrion Biosciences is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.

Cell Culture and Characterization

  • Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...

In Vitro Assays

  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression

In Vitro Pharmacology

  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
  • In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
  • Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.

In Vitro Toxicology

  • Cardiac Channels Measure the arrhythmia producing potential of test compounds.
  • Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
  • hERG Inhibition Measure the arrhythmia-producing potential of test compounds.

Safety Pharmacology

  • Microelectrode Array Neurotoxicity Assays Use microelectrode array to measure neurotoxicity-related activities.
  • Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
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Other services

  • Nerve-On-A-Chip Neurotoxicity Assay Employ the micro-engineered nerve-on-a-chip technology to predict neurological safety and efficacy early in the drug development pipeline.
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Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Cambridge 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Metrion Biosciences, a UK-based Contract Research Organization, is a wholly owned business unit of Xention Limited. It has been established from Xention’s drug discovery unit and provides customers with access to a range of high quality ion channel screening services on a fee-for-service or collaboration basis.

Website
www.metrionbiosciences.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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