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Matterworks

Matterworks is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

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Type of company: Small business

Agricultural Sciences Compliance and Quality Control Measures

Exposure Tests which assess human health impact upon exposure of product.
Pesticide Product Testing Use laboratory assays to evaluate the efficacy, safety and selectivity of a pesticide under GLP standards.
Product Properties Determination of physical and chemical properties of product
Residue Chemistry Pesticide residue and tolerance testing.

Agricultural Sciences Research & Development

Agrochemical Identification Product identification and composition of pesticides; which includes fungicides, insecticide, herbicides and nematicides analysis.
Animal Feed Supplements Test for mineral nutrients and medicinal compounds for the prevention or control of disease.
Chemical and Physical Determination of chemical and physical properties of pesticide product.
General Agrochemical Compound Library Find potential compound candidates for agrochemical or agro-product research and development.
Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties
Molecular Markers Use of molecular diagnostics to analyze biological markers in the genome and proteome.

Show all 7 in Agricultural Sciences Research & Development 1 more

Pesticide Conduct field trials to determine environmental risk assessment and associated studies pertaining to residue, efficacy, soil dissipation and the like.

Biomarkers

Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body

Show all 26 in Biomarkers 20 more

Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
Complete Metabolic Panel Testing Detect electrolyte or glucose imbalance to identify or monitor related disorders.
Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Oxidized Low Density Lipoproteins (LDL) Testing Identify the risk for metabolic syndrome and the development of associated diseases.
Peptide Bioanalysis Analyze the structure of Peptides.
Peritoneal Fluid Analysis Determine the cause of fluid accumulation in the peritoneal space.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Spatial Metabolomics The study of the spatial distribution and localization of metabolites within biological tissues using advanced imaging and analytical techniques.

Show all 179 services 163 more

Cell Culture and Characterization

Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
Spent Media Analysis Measure chemical alterations, such as variations in amino acids, glucose, contaminants, and metabolites, in a cell culture medium throughout the culturing process.

Chemical and Compound Analysis

Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
Bioanalysis Bioanalysis involves the determination of the concentration of test compounds in biological samples including plasma, urine, an...
Chemical Stability Measure the stability of small molecules in solution.
Compound Integrity Analyze the identity and purity of small molecule drug candidates.
Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.

Show all 17 in Chemical and Compound Analysis 11 more

Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Liquid Chromatography Separate substances using a mobile and stationary phase.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Chemical and Compound Testing

Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.
Product Testing Ensure product quality standards are met.

Chemistry, Manufacturing and Controls (CMC)

Analytical Development and Validation Request services related to Analytical Development and Validation
API and Drug Product Stability Testing API and Drug Product Stability Testing.
Bulk Manufacturing Find facilities for large-scale mass production.
Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.

Show all 7 in Chemistry, Manufacturing and Controls (CMC) 1 more

Impurities in Drugs Risk Assessment Create a risk-based control strategy to determine any toxic elemental impurities that may be present in human medicines.

Clinical Consulting

Bioanalysis Consulting Expert advice to properly and effectively discover, evaluate, and measure chemical or biological materials.
Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

Clinical Trials

BioAnalytical Laboratory Services Bioanalytical laboratory services provide essential testing to quantify drugs, metabolites, and biomarkers in biological samples (blood, urine, tissue) to support preclinical and clinical drug development

Data Science/Bioinformatics

Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Clinical Data Analysis Analysis that helps you make sense of your clinical data
Clinical Data Science and Modeling A process that helps make sense of your clinical data
Clinical Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects
Clinical Responder Analysis, Patient Stratification The process of identifying patients that are more likely to respond positively to a drug.
Discovery Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.

Show all 34 in Data Science/Bioinformatics 28 more

Discovery Biomarker Analytics An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Discovery Compound Screening Analytics Screening of an entire compound library directly against the drug target or in a more complex assay.
Discovery Data Analysis Analysis that helps you make sense of your discovery data
Discovery Data Integration The process of combining different complex data types together to make it easier to understand or analyze.
Discovery Data Science and Modeling A process that helps make sense of your discovery data
Discovery Databases Databases specifically designed for drug discovery use.
Discovery Drug Response Simulation Analytics Simulation of how a drug responds in different environments, from molecular to population studies.
Discovery In Silico Drug Dynamics Develop In Silico model of a drug candidate with a biological system with applications such as Pro-drug Predictions, ADME-PK Due Diligence, Brain-Barrier Permeability Simulation, Drug Absorption Simulation, In Silico...
Discovery In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your Genomics/Transcriptomics data
Discovery In Silico Proteome Analysis Used to understand the global protein environment, specifically drug-protein interactions.
Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Discovery Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
Discovery Predictive Analytics Analytical approaches to predict how a drug target behaves in a given environment.
Discovery Software Tools Software designed to serve the needs of discovery research groups.
Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
Proteome Data Analysis Find tools for analysis of homology and similarity, protein function and structural properties.
Translational Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.
Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Translational Data Analysis Analysis that helps you make sense of your translational data
Translational Data Curation Generally, human curation of acquired data to assess the quality and reliability of different data.
Translational Data Harmonization and Integration Process to combine different data together for better understanding and analysis of the integrated data.
Translational Data Knowledge Extraction Analytical approaches to extract data from different sources like publications, databases, etc. 
Translational Data Management A process that includes acquiring, validating, storing, protecting, and processing required data to ensure the accessibility, reliability, and timeliness of the data.
Translational Data Science and Modeling A process that helps make sense of your translational data
Translational In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your omics data
Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Translational Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
Translational Software tools Software designed to serve the needs of translational research groups.

Discovery Chemistry

Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Discovery Molecular Modeling and Simulation Analytics Computational methods to model and study the behavior of molecules, from small chemical systems to large biological molecules.
Extractable and Leachable Assessment Quantify potential impurities from container closures & packaging.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

Show all 11 in Discovery Chemistry 5 more

Leachable and extractable testing Leachable and extractable testing
Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Natural Product Screening Screen large natural product collections for therapeutic activity.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Drug Development

Bioinformatics Consulting Consulting Services for the science of collecting and analyzing complex biological data
Cellular Immunology Consulting Immunological activities of cells in experimental or clinical situations
Large Molecule Drug Development Consulting Develop large molecule drugs and complex biologics that have a therapeutic effect.
Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.

Farm & Livestock Solutions

Animal Feed Analysis Test the content and quality of nutrients and biologically active substances in animal feeds. Some analysis that is conducted on feed include; dry matter, crude ash, ash insoluble in acid (sand), crude protein, crude...
Composite Soil Sampling Obtain multiple and random soil samples to create a single larger specimen for analysis.
Soil Acidity Testing Determine soil acididty to assess plant suitability or amend soil pH.
Soil Alkalinity Testing Determine soil alkalinity to assess plant suitability or amend soil pH.
Soil Environmental Testing Measure environmental contaminants using soil sample analysis.
Soil Fertility Testing Evaluate soil growth potential based on nutrient deficiencies or toxicities.

Show all 10 in Farm & Livestock Solutions 4 more

Soil Organic Matter Testing Evaluate soil organic matter to enable long-term soil health and optimal crop yield.
Soil Salinity Testing Measure total soluble salt content of a soil sample to inform corrective action.
Soil Soluble Salts Test Identify the soluble salt components of a soil sample to direct remedial steps.
Soil Testing Use various tests to characterize a soil sample.

In Vitro ADME

Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
In Vitro ADME in Vitro ADME services

Show all 20 in In Vitro ADME 14 more

Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.
Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
Non Isotopic Labeling Track unlabeled macromolecules through a metabolic pathway or cell.
Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
Reference Standards Find reference standards for assays, tests and services.

In Vitro Assays

Glucose Release Assay Determine free glucose levels in biological samples.
Glycobiology Study the structure biosynthesis and biology of carbohydrates
HTS Assay Development Develop assays to use in high throughput screening.
Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.

In Vitro Pharmacology

High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.

Protein Sciences

LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
Peptide Discovery Identifying and developing new peptides.
Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
Phosphorylation Analysis Identify phosphorylation sites in target proteins.
Protein Identification Uncover or confirm the identity of a protein.

Show all 12 in Protein Sciences 6 more

Protein mapping Interrogate the entire sequence of a protein.
Protein Sequencing Determine the amino acid sequence of protein or peptide.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.
Quantitative MS Quantify small and large molecules in the pg/ml range
SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.

Scientific Data Services

Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
Large Language Models Use of Large Language models in target discovery, clinical trial design and development, analysis of clinical trial data and regulatory submissions. Services are tailored to the problem, specific context of biopharma.
Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
Marker Analyses Identify associations between genetic markers and traits of interest to determine markers responsible for human diseases.
Metabolomics Data Analysis Use metabolites to identify any potential biomarkers or novel therapeutic targets that may play a role in the mechanisms responsible for the progression of a disease.

Show all 9 in Scientific Data Services 3 more

Microbiome Data Analysis Determine the population composition of a microbial community and analyze its contribution to human or animal health.
Molecular Phylogenetics Analyze hereditary molecular differences in genomic sequences to compare genomes.
Omics Informatics Consulting Services for the analysis of large-scale molecular data sets.

Testing Services

Characteristic Testing Characterization of physical and chemical properties of raw materials
In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
Raw Material Microbiological Testing Examples of which include Microbial Content using USP <61> and <62> and other standards, LAL Endotoxin, Ames Mutagenicity and Sterility.

United States Somerville 2 sites

Professional associations: MassBio
Website: www.matterworks.ai

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