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Shamrock Structures
Shamrock Structures is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Chemical and Compound Analysis
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Show all 12 in Discovery Chemistry
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
DNA & RNA
- Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.
Protein Sciences
- X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Shamrock Structures offers protein crystallography research services, including construct design, DNA cloning, protein expression and purification, crystallization, synchrotron X-ray data collectiona and structure determination.
- Website
- www.shamrockstructures.com
Work with Shamrock Structures on Scientist.com
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