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BD Biosciences

BD Biosciences is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 1
Countries 1

Logo BD (company), via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Antibodies

  • Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
  • Antibody Products Purchase antibody, antibody pair kit or ELISA kit.

Biomarkers

  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
  • Single Cell Isolation Isolate single cells for subsequent single-cell analysis.

Cell Culture and Characterization

  • Bacterial Cell Culture Culture and Grow bacterial cells.
  • Cell Culture Culture primary or immortalized cell lines.
  • Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
  • Spent Media Analysis Measure chemical alterations, such as variations in amino acids, glucose, contaminants, and metabolites, in a cell culture medium throughout the culturing process.
  • Yeast Cell Culture Grow yeast strains or species.

Chemical and Compound Analysis

  • Sample Bioanalysis Determination of concentration of an analyte in biological sample.

Discovery Chemistry

  • Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...

Disease Models

  • Receptor Occupancy Models Determine the effective dose and concentration needed to reach effective levels in a given tissue.
Show all 31 services 19 more

DNA & RNA

  • RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
  • Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.

In Vitro ADME

  • Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
  • CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
  • CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
  • Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
  • HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
  • Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Show all 7 in In Vitro ADME 1 more
  • Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.

In Vitro Assays

  • Assay Development Construct or create new assays or modify existing ones.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.

Product Orders

  • Kits and Reagents Submit a request to multiple vendors for kits and reagents.

Protein Sciences

  • Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
  • Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
  • Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
  • Protein Binding Determine drug-protein binding interactions
  • Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.

Testing Services

  • Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.

Service areas:

Biology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States San Jose 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

BD Biosciences offers ADME/Tox services, cell analysis and reagent services, bioprocessing media and supplement services, custom coating services and microplate barcoding services.

Website
www.bd.com/biosciences

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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