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RoukenBio
RoukenBio is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse
- Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
- Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
Show all 9 in Antibodies
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
- Immunodetection Use antibodies to identify a protein or antigen.
- Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Show all 10 in Biomarkers
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
- Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- T Cell Epitope Characterization Evaluate the potency and immunodominance of T-cell epitopes within a molecule.
Show all 74 services
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Construction Create new recombinant cell lines to exact specifications.
- Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
Show all 8 in Cell Culture and Characterization
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
- Stem Cell Methodologies Study Stem Cell characteristics.
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Chemistry, Manufacturing and Controls (CMC)
- Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
DNA & RNA
- Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
- Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
Drug Development
- Cellular Immunology Consulting Immunological activities of cells in experimental or clinical situations
Human Biological Samples
- Cell Line and Cellular Services Promotion for Cells and Cell lines
- Inducible Expression Cell Lines Inducible expression cell lines let researchers turn gene activity on or off using external chemical or physical signals
- Patient Derived Tumoroids 3d tumoroids generated from patient derived tumour tissue
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Show all 11 in In Vitro Assays
- Cell Proliferation Measure cell number, cell viability and cell division.
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
- SARS-CoV-2 (COVID-19) Assays Search for Available SARS-CoV-2 Assays
In Vitro Pharmacology
- Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Assays Use biochemical, cell based or in vivo assays to measure CTLA-4 receptor activity.
- HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
Show all 11 in In Vitro Pharmacology
- Mammalian Target of Rapamycin Complex Assays Use biochemical, cell based or in vivo assays to measure mTORC enzyme activity.
- Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
- Target Characterization Characterize potential drug targets during the drug discovery process.
- Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.
- Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
- Protein Binding Determine drug-protein binding interactions
Show all 9 in Protein Sciences
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Safety Pharmacology
- Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.
Other services
- Human Dendritic Cell (hDC) Model Test and validate the immune-modulating compounds in DC immune pathway models.
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- Website
- rouken.bio
Where it operates
Sites by country, with the cities in each.
-
United Kingdom 2 sites
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