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Genemarkers
Genemarkers is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Immunodetection Use antibodies to identify a protein or antigen.
Biomarkers
- Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Microfluidics-Based Biomarker Isolation and Detection Isolate and detect rare biomarkers in blood samples, such as CTCs, cfDNA, and exosomes.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Show all 7 in Biomarkers
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Show all 7 in Cell Culture and Characterization
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Show all 64 services
Chemical and Compound Testing
- Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.
- Product Testing Ensure product quality standards are met.
Clinical Consulting
- Clinical Trial Recruitment Recruitment, enrollment and retention of patients for clinical trials.
DNA & RNA
- Amplified Fragment Length Polymorphism Detection Detect DNA polymorphisms based upon restriction enzyme digestion and PCR.
- DNA Extraction Extract DNA from an original source.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
- mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
- PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
Show all 11 in DNA & RNA
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
Effectiveness
- In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
Human Biological Samples
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Cell Lysates For requesting human Cell lysates.
- Human Epithelial Cells Human epithelial cells are the most abundant cell type in the body and form the outer layer of skin and line various internal organs, including the digestive and respiratory tracts.
- Human Melanocytes Human Melanocytes are pigment-producing cells primarily found in the skin, hair follicles, and eyes
- Human Saliva Acquire fresh/frozen normal saliva based on patient demographics and history.
In Vitro ADME
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Show all 10 in In Vitro Assays
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- In Vitro Human Cell Assays Request in vitro human cells for assays
- In Vitro SPF (Sun Protection Factor) Testing Use in vitro test methods to measure the UVA protection performance of sun protection products.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
- Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
- HepaRG Cells Obtain terminally differentiated and cryopreserved hepatic cells that retain many characteristics of primary human hepatocytes.
Model Development
- Custom Model Development Develop a custom disease model.
Product Development
- Personal/Consumer Care Product or Service Request relating to the creation, testing or manufacturing of a personal care/consumer health/cosmetic product, ingredient or raw material.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Mutation Data Profiling Guide treatment decisions in cancer based on the identification of genomic mutations .
- Pharmaco-genomics Genetic polymorphism contribution to inter-individual variability in drugs' responses and/or adverse events.
Testing Services
- Collagen Production Test Test the regenerative ability of the skin under the influence of the test sample.
- Consumer Care Testing and Substantiation Test personal care products using analytical, in vitro, and microbial test services
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
- OECD 435: Skin Corrosion Test - Membrane Barrier Method Use in vitro models to determine whether a cosmetic product or ingredient can cause skin corrosion.
- OECD TG 492: Ocular Irritation Testing Use in vitro skin models to determine whether a product can cause dermal sensitization (e.g. EpiOcular Eye Irritation Test - EIT)
- Skin Lightening Product Test Measure qualitative and quantitative changes in skin pigmentation under the influence of the test sample.
Service areas:
Biology
Where it operates
Sites by country, with the cities in each.
-
United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Genemarkers offers nucleic acid isolation, gene expression profiling, microRNA expression profiling, genotyping, and pathway analysis services.
- Website
- www.genemarkersllc.com
Supplier diversity
SAM.gov small-business designations
Woman-owned
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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