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Biofidus AG
Biofidus AG is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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1
Countries
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
Biomarkers
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
- Protein Glycosylation Mapping Technique Map glycosylation sites in proteins using liquid chromatography and mass spectrometry.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell Culture Culture primary or immortalized cell lines.
- Spent Media Analysis Measure chemical alterations, such as variations in amino acids, glucose, contaminants, and metabolites, in a cell culture medium throughout the culturing process.
Chemical and Compound Analysis
- Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
- Chemical Stability Measure the stability of small molecules in solution.
- Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
- Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Show all 15 in Chemical and Compound Analysis
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Viscosity Testing Evaluate the fluid flow properties of liquids for product evaluation and quality control.
Show all 60 services
Chemistry, Manufacturing and Controls (CMC)
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- ICH-compliant stability testing Perform ICH-compliant stability testing
Discovery Chemistry
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
DNA & RNA
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
- NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
In Vitro ADME
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
In Vitro Assays
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Glycobiology Study the structure biosynthesis and biology of carbohydrates
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
Protein Sciences
- Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
- Carbohydrate Isolation Obtain pure monosaccharides, pure polysaccharides or related derivatives from samples.
- Carbohydrate Isolation Protocol Development Design and optimize protocols for carbohydrate isolation.
- Carbohydrate Structure Characterization Use analytical tools to elucidate carbohydrate structure and physiochemical properties.
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
- Phosphorylation Analysis Identify phosphorylation sites in target proteins.
Show all 15 in Protein Sciences
- Protein Identification Uncover or confirm the identity of a protein.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Sequencing Determine the amino acid sequence of protein or peptide.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Elevated Temperature Stability Determine the stability of a product at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Website
- www.biofidus.com
Where it operates
Sites by country, with the cities in each.
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Germany 1 site
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