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University of the Sciences Industrial Pharmacy Laboratory

University of the Sciences Industrial Pharmacy Laboratory is listed as an academic core research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Academic core

Chemical and Compound Analysis

  • Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
  • GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.

Clinical Trials

  • Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.

Food Safety & Regulations

  • Water Activity Determine water activity in consumer healthcare products involving a USP or FCC monograph.

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
  • Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
  • Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
  • Nasal Permeability Test for passive diffusion and active transport in nasal permeability models.
  • Ocular Permeability Measure passive diffusion and active transport of drugs across confluent ocular epithelial cells.
  • Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
Show all 7 in In Vitro ADME 1 more
  • Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
Show all 20 services 8 more

In Vivo Pharmacokinetics

  • Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
  • Elevated Temperature Stability Determine the stability of a product at elevated temperature.
  • Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
  • Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
  • Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
  • Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Philadelphia 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

The Industrial Pharmacy Laboratory (IPHL) at University of the Sciences is fully equipped for all aspects of pre-clinical pharmaceutical development including analytical, pre-formulation, formulation and stability studies on small and large molecules.

Website
www.usciences.edu/research/industrial-pharmacy-lab/index.html

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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