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DeepkinetiX
DeepkinetiX is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Biomarkers
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
Cell Culture and Characterization
- Microphysiological system (MPS)/organoid analytics microTMA produced from fixed microtissues (MPS)
- Microphysiological Systems/organoid transcriptomics Microphysiological Systems/organoid transcriptomics
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- Clinical Responder Analysis, Patient Stratification The process of identifying patients that are more likely to respond positively to a drug.
Disease Models
- Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
Effectiveness
- Bioequivalence Studies for Veterinary Drugs Assess the expected biological equivalence of two proprietary preparations of a veterinary drug.
- In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
Human Biological Samples
- Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...
Show all 51 services
In Vitro ADME
- Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
- Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Human Blood Brain Barrier on a Chip (BBBoC) Create a blood–brain barrier multicellular model to test drug delivery to the brain.
Show all 13 in In Vitro ADME
- In Vitro ADME in Vitro ADME services
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Multidrug Resistance Identify potential causes of drug-drug interactions.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
- Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
In Vitro Assays
- 3Screen™ 3D In Vitro Services 3Screen™ Platform enables complete 3D cell culture characterization.
- In Vitro Human Cell Assays Request in vitro human cells for assays
- Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
In Vitro Pharmacology
- In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Hemolysis Assay Evaluate the toxicity of a drug, metabolite or excipient by hemolytic release of hemoglobin in the plasma.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vitro Toxicology
- Toxicology- in vitro Toxicity testing and model development in vitro on developmental and adult neurotoxicity
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
- In Vivo Radiolabeled Metabolism Determine the qualitative and quantitative metabolism and/or degradation of an active ingredient in animals.
- Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.
In Vivo Pharmacokinetics
- In Vivo Immunogenicity Study An in vivo immunogenicity study evaluates a substance's ability to trigger an immune response within a living organism.
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Integrated In Vivo Services Package Process an entire In Vivo Project including: Dose Formulation, PK Screening, ADME-Profiling, Toxicology, Safety Pharmacology, DART, IND Filing from our bundle of suppliers.
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Medical Communications
- Pharmacodynamic/ Pharmacokinetic Reports Create Pharmacodynamic/ Pharmacokinetic reports to report to the appropriate regulatory bodies.
Model Development
- In Silico PK-PD Modeling Quantitative modeling and simulations correlation of pharmacokinetic and pharmacodynamic endpoints in support of preclinical and clinical development.
Oncology Models
- Ex-Vivo PDX Screening Ex-vivo PDX screening is used to evaluate the effectiveness of various drugs on tumor cells.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Pharmacology
- In Vivo Pharmacology Study the effects of drug candidates in animal models
Protein Sciences
- Protein Binding Determine drug-protein binding interactions
Real World Evidence & Data
- Clinical Phenotype Data Obtain phenotypic data and observations on patients such as the clinical manifestation of the disease, clinical and behavioral parameters, symptoms, and laboratory test results.
Scientific Data Services
- Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Testing Services
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
- Website
- deepkinetix.com
Where it operates
Sites by country, with the cities in each.
-
United States 1 site
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