- Supplier site
- Group of sites (click to zoom)
Scientist.com supplier network (site locations)
Research supplier
MB Biosciences
MB Biosciences is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country.
Sign in to Scientist.com to open this supplier in your organization's marketplace.
Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Biomarkers
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
In Vitro ADME
- Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
- Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Show all 9 in In Vitro ADME
- Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Multidrug Resistance Identify potential causes of drug-drug interactions.
Show all 39 services
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
In Vitro Pharmacology
- In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
- HepaRG Cells Obtain terminally differentiated and cryopreserved hepatic cells that retain many characteristics of primary human hepatocytes.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Model Development
- Fresh Functional Human Tissue Vascular Permeability Assays Use fresh functional human tissue to assess vascular permeability with various compounds.
Oncology Models
- Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
- Oncology Xenografts Xenografts derived from oncological samples.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
REACH Services
- OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
- OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
- OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
- OECD 475: Mammalian Bone Marrow Chromosomal Aberration Test The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese...
- OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Testing Services
- Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
-
United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
MB Biosciences, a privately-owned biotechnology company, provides animal organ-derived primary cell products and animal model services. Driven by a passion for quality and innovative science, the goal of our scientists and staff is to provide you with the best primary cells, specialty cell culture system, and animal models for your research needs. We also customize solutions to your specific research problems. We specialize in customized collection, isolation, and testing of animal organ-derived primary cells and other biological products. Our extensive isolation schedule and well...
Show the full description
MB Biosciences, a privately-owned biotechnology company, provides animal organ-derived primary cell products and animal model services. Driven by a passion for quality and innovative science, the goal of our scientists and staff is to provide you with the best primary cells, specialty cell culture system, and animal models for your research needs. We also customize solutions to your specific research problems.
We specialize in customized collection, isolation, and testing of animal organ-derived primary cells and other biological products. Our extensive isolation schedule and well controlled procedures ensure a readily-available inventory of high-quality and consistent primary cells as well as biological products for advanced bio-medical research. We also provide high quality in vivo and in vitro services
MB Biosciences is committed to working with you to develop custom products that aids in experimental efficiency and effectiveness. If there is a product or service that we are not currently offering, we’d be happy to customize cell isolation products and animal models to meet your specific needs. Backed by many years of cell separation and animal model expertise from our scientists, we will work with you and provide you the best products and services.
- Website
- www.mbbiosciences.com
Work with MB Biosciences on Scientist.com
For prices, more details, or to contact MB Biosciences, visit Scientist.com.
Sign in to Scientist.com to open this supplier in your organization's marketplace.