ActivSignal

ActivSignal is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

Antibodies

Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
Immunodetection Use antibodies to identify a protein or antigen.
Membrane Proteome Array (MPA) Services Use a high-throughput, cell-based platform for profiling antibody specificity that targets human membrane proteins.

Biomarkers

Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
Biomarker Screening Biomarker testing analyzes tissue, blood, or fluid samples to identify specific genes, proteins, or molecules that indicate disease, particularly cancer.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.

Show all 11 in Biomarkers 5 more

Endocrine Assays Use biochemical, cell based or in vivo assays to measure the concentration of hormones.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.

Cell Culture and Characterization

Microphysiological Systems/organoid transcriptomics Microphysiological Systems/organoid transcriptomics
Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Show all 45 services 33 more

Chemical and Compound Analysis

Sample Bioanalysis Determination of concentration of an analyte in biological sample.

Disease Models

Inflammation Models Measure therapeutic endpoints in animal models for inflammation.

In Vitro Assays

Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
HTS Assay Development Develop assays to use in high throughput screening.
In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.

Show all 10 in In Vitro Assays 4 more

Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

In Vitro Pharmacology

Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
Human BCL Assays Use biochemical, cell-based or in vivo assays to measure BCL activity.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Excitotoxicity Models Use in vitro models to measure therapeutic endpoints associated with excitotoxic pathology.
In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.

Show all 8 in In Vitro Pharmacology 2 more

Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation
Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.

Protein Sciences

Cytokines Find recombinant cytokines or cytokine assays.
Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Kinase Panel Assays Work with service providers offering biochemical assays to assess the activity of multiple protein kinases simultaneously to identify and characterize kinase inhibitors, understand selectivity trends, and assess...
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.

Safety Pharmacology

Cytokine Release Syndrome In Vivo assessment of cytokine release syndrome liability in a humanized mouse
Safety Screen Panel Assays Safety Pharmacology safety screen panel assays enable early identification of significant off-target interactions with your compound(s)

Website: ActivSignal.com

United States Natick 2 sites

Work with ActivSignal on Scientist.com

For prices, more details, or to contact ActivSignal, visit Scientist.com.

View on Scientist.com