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SBH Sciences
SBH Sciences is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Biomarkers
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Cell Culture Culture primary or immortalized cell lines.
- Insect Tissue Culture Grow insect cells.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
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Disease Models
- Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
In Vitro Pharmacology
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
- Tubule Epithelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the kidney.
Product Orders
- BioTx General Biotherapeutics analyze therapeutics and drugs via biological means and recombinant DNA. Pre-clinical sample bioanalysis and le...
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Protein Binding Determine drug-protein binding interactions
- Protein Engineering Alter the features or properties of a protein for a specific purpose.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
SBH Sciences provides cell-based discovery and preclinical process development services based on its expertise in cell culture, biologic production, and biomarker development. The company’s extensive, innovative cell based cytokine and cancer drug profiling assays provide time and cost effective tools for screening drug candidates and optimizing leads. SBH Sciences has comprehensive preclinical production capabilities for biologics, from DNA to final pure active product. The company’s expertise provides a rapid path to biomarker discovery and optimization. SBH Sciences has a strong track...
Show the full description
SBH Sciences provides cell-based discovery and preclinical process development services based on its expertise in cell culture, biologic production, and biomarker development. The company’s extensive, innovative cell based cytokine and cancer drug profiling assays provide time and cost effective tools for screening drug candidates and optimizing leads. SBH Sciences has comprehensive preclinical production capabilities for biologics, from DNA to final pure active product.
The company’s expertise provides a rapid path to biomarker discovery and optimization. SBH Sciences has a strong track record of quality, service, and on-time delivery through over 16 years working with over 120 therapeutic and diagnostic companies. Our array of cytokine bioassay service is the most comprehensive in the US and includes over 280 bioassays that can accelerate discovery and biopharma development programs. Moreover, our proprietary processes have achieved commercial production of 30 highly purified recombinant cytokines and 33 monoclonal antibodies, currently sold to the scientific community worldwide. SBH Sciences is based in Natick, MA.
Raphael Nir, Ph.D.
President & CSO
SBH Sciences
[removed] Ext. 214
www.sbhsciences.com
- Website
- www.sbhsciences.com
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