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PBL Assay Science
PBL Assay Science is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- AlphaLISA Quantification of analytes with high sensitivity, wider dynamic range and no wash steps involved.
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
Show all 11 in Antibodies
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
- Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
- Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
- Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
Biomarkers
- Autoantibody Testing Screen for the presence of an autoimmune disorder.
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Show all 22 in Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Interferon Gamma Release Assay Use in vivo or in vitro assays to measure the cell-mediated immune response to an infectious agent.
- Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
- Myeloperoxidase Testing Detect inflammatory markers and determine the risk for atherosclerosis or arterial plaque rupturing.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
- Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
- Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Show all 87 services
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Chemical and Compound Analysis
- Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Disease Models
- Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
- Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
Show all 7 in Disease Models
- Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
- Fully Automated Assays Develop and perform assays that require no manual steps
Show all 10 in In Vitro Assays
- HTS Assay Development Develop assays to use in high throughput screening.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
In Vitro Pharmacology
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
Show all 18 in Protein Sciences
- Native Protein Purification Purify native proteins from sources such as tissue & serum.
- PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
- Protein Binding Determine drug-protein binding interactions
- Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Products Find native and recombinant proteins and peptides.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Testing Services
- OECD 442D: ARE-Nrf2 Luciferase Test An in vitro test method (KeratinoSensTM and/or LuSens) that models the second key event in the Adverse Outcome Pathway for Dermal Sensitization.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
PBL Assay Science works hand in hand with researchers to help solve their most difficult problems. We have the ability and expertise in Assay Science that enables scientists to successfully conduct research. For twenty-three years PBL has grown not only in the number of products we offer, in the space we occupy, and in the number of our employees but, most importantly, we have developed a robust Assay Science knowledge base and an ability to successfully complete projects. Our beginnings are as a major provider of products, services, information, and know-how related primarily...
Show the full description
PBL Assay Science works hand in hand with researchers to help solve their most difficult problems. We have the ability and expertise in Assay Science that enables scientists to successfully conduct research. For twenty-three years PBL has grown not only in the number of products we offer, in the space we occupy, and in the number of our employees but, most importantly, we have developed a robust Assay Science knowledge base and an ability to successfully complete projects.
Our beginnings are as a major provider of products, services, information, and know-how related primarily to interferons. The pioneering interferon research conducted by our founder, Sidney Pestka, M.D., and his many colleagues and collaborators reflects decades of exploration into interferon's applications in medicine. Over the years we have grown from start-up to well respected company, employing state-of-the-art technology in conducting assay services and manufacturing world-class products for scientists around the globe each day. Recognizing that our research, our products, and our services have moved beyond interferon into other cytokines and biological materials, we have grown from the “InterferonSource” into an Assay Science company. Let us help you solve your most difficult problems.
- Website
- www.pblassaysci.com
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