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Hooke Laboratories
Hooke Laboratories is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Cell Culture and Characterization
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Disease Models
- Acute Lung Injury Models Measure therapeutic endpoints in animal models of acute lung injury.
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
- Autoimmune Models Measure therapeutic endpoints in animal models with autoimmune disorders.
- Demyelination Models Measure therapeutic endpoints in animal models with demyelination pathology.
- Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
Show all 12 in Disease Models
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
- LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
- Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.
Show all 26 services
Model Development
- PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
Non-Human Biospecimen
- Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Mouse Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Pharmacology
- In Vivo Pharmacology Study the effects of drug candidates in animal models
- In Vivo Services Suppliers that house animals of any species.
Other services
- Biological Material For requesting cells and other propagatable material.
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
We are 100% focused on rodent in vivo research. We will do as much or as little work as you need with no up-front investment or setup effort from you. +Collagen-induced arthritis (CIA)+ +Experimental autoimmune encephalomyelitis (EAE)+ MOG35-55/CFA-induced EAE in C57BL/6 mice PLP139-151/CFA-induced EAE in SJL mice Adoptive transfer EAE in SJL mice Adoptive transfer EAE in C57BL/6 mice Our focus is on inflammation models in mice and rats; we specialize in EAE and CIA. Our staff has extensive experience in: Evaluation of potential therapeutic compounds in models of autoimmune diseases...
Show the full description
We are 100% focused on rodent in vivo research. We will do as much or as little work as you need with no up-front investment or setup effort from you.
+Collagen-induced arthritis (CIA)+
+Experimental autoimmune encephalomyelitis (EAE)+
- MOG35-55/CFA-induced EAE in C57BL/6 mice
- PLP139-151/CFA-induced EAE in SJL mice
- Adoptive transfer EAE in SJL mice
- Adoptive transfer EAE in C57BL/6 mice
Our focus is on inflammation models in mice and rats; we specialize in EAE and CIA.
Our staff has extensive experience in:
Evaluation of potential therapeutic compounds in models of autoimmune diseases
Development and optimization of new inflammation models
We are continuously introducing additional models in other areas of inflammation research.
Our Services
Hooke can perform all elements of your study, including:
- Disease induction
- Efficacy testing
- Clinical observation
- Blood & histological analysis
- FACS analysis of cellular infiltrates
- Statistical analysis
- Report preparation
- Interpretation of results
+Why Hooke?+
Quality & Price
Our 100% focus on rodent in vivo research lets us work efficiently, and our low-cost rodent facility in Lawrence, Massachusetts (30 minutes north of Cambridge) keeps our prices very competitive, while delivering first-class science.
Flexibility
We can do as much or as little work as you need – with no up-front investment or setup effort from you. You can even make changes after we've started your study; we want our customers to feel just as comfortable working with us as with their own in-house scientists.
Expertise
Each model we offer has been established in our lab by an experienced scientist with multiple published papers in that research area. In addition to running your study, we can provide valuable expertise and interpretation of results.
By specializing in rodent in vivo work, we can do the job more efficiently and at less total cost to you. We are committed to providing first class science at very competitive prices.
Please see http://hookelabs.com/services/cro/ for more details.
- Website
- hookelabs.com
Supplier diversity
SAM.gov small-business designations
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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