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Research supplier
Javelin Biotech
Javelin Biotech is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Disease Models
- Bone Models Measure therapeutic endpoints in animal models of bone disorders.
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
Human Biological Samples
- Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
In Vitro ADME
- Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
- Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Human Blood Brain Barrier on a Chip (BBBoC) Create a blood–brain barrier multicellular model to test drug delivery to the brain.
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
In Vitro Pharmacology
- In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
Show all 18 services
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Scientific Data Services
- Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
Testing Services
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
Other services
- Human Small Airway-On-a-Chip Study human lung inflammation and drug responses in vitro.
- Nerve-On-A-Chip Neurotoxicity Assay Employ the micro-engineered nerve-on-a-chip technology to predict neurological safety and efficacy early in the drug development pipeline.
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Preclinical drug testing platform integrating Organ-on-Chip (OoC) technologies and computational biology to optimize lead selection and clinical trial design
- Professional associations
- MassBio
- Website
- www.javelinbio.com
Work with Javelin Biotech on Scientist.com
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